HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: SEM4D (Q92854)
Semaphorin-4D (A8) (BB18) (GR3) (CD antigen CD100)
Gene: SEMA4D

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001934 - positive regulation of protein phosphorylation GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 862
+	Hs
		348840 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SEM4D_HUMAN (1-862): 0: 1062: 100.00
+	Hs
		349625 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SEM4C_HUMAN (5-657): 0: 686: 40.88
+	Hs
		348909 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SEM4C_HUMAN (5-657): 0: 686: 40.88
+	Hs
		1070385 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		SEM4C_HUMAN (5-657): 0: 686: 40.88
+	Hs
		350524 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SEM4C_HUMAN (5-657): 0: 686: 40.88
+	Hs
		914341 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		SEM4C_HUMAN (5-657): 0: 686: 40.88
+	Mm
		914512 RB11A_MOUSE (4-184): 2.43e-72: 219: 33.88		SEM4A_MOUSE (9-682): 0: 584: 34.76
+	Hs
		348915 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SEM6A_HUMAN (1-725): 1.07e-168: 518: 26.07
+	Hs
		350373 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SEM6D_HUMAN (3-585): 2.26e-172: 529: 29.73
+	Hs
		350538 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SEM6A_HUMAN (1-725): 1.07e-168: 518: 26.07
+	Hs
		195964 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PLXB1_HUMAN (6-710): 3.9e-144: 472: 17.17