HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: NUMBL (Q9Y6R0)
Numb-like protein (Numb-related protein) (Numb-R)
Gene: NUMBL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30442766, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 609
+	Hs
		349776 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		NUMBL_HUMAN (1-609): 3.31e-87: 285: 100.00
+	Hs
		349044 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		NUMBL_HUMAN (1-609): 3.31e-87: 285: 100.00
+	Hs
		1070492 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		NUMBL_HUMAN (1-609): 3.31e-87: 285: 100.00
+	Hs
		914507 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		NUMBL_HUMAN (1-609): 3.31e-87: 285: 100.00
+	Hs
		349190 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		NUMB_HUMAN (42-609): 2.54e-68: 235: 46.87
+	Hs
		348573 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		NUMB_HUMAN (42-609): 2.54e-68: 235: 46.87
+	Hs
		833596 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		NUMB_HUMAN (42-609): 2.54e-68: 235: 46.87
+	Hs
		349976 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		NUMB_HUMAN (42-609): 2.54e-68: 235: 46.87
+	Hs
		833561 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		NUMB_HUMAN (42-609): 2.54e-68: 235: 46.87
+	Hs
		833569 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		NUMB_HUMAN (42-609): 2.54e-68: 235: 46.87
+	Hs
		350414 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ANS1A_HUMAN (7-259): 2.46e-57: 210: 20.23
+	Mm
		1206680 RAB1B_MOUSE (4-187): 1.74e-73: 221: 31.96		ANS1B_MOUSE (7-256): 3.08e-59: 216: 21.32
+	Hs
		253561 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		CAPON_HUMAN (68-316): 6.44e-39: 151: 19.05
+	Hs
		253519 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		CAPON_HUMAN (68-316): 6.44e-39: 151: 19.05
+	Hs
		297805 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		K0754_HUMAN (173-497): 2.24e-24: 111: 11.25
+	Hs
		297829 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		K0754_HUMAN (173-497): 2.24e-24: 111: 11.25
+	Hs
		297806 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		K0754_HUMAN (173-497): 2.24e-24: 111: 11.25
+	Hs
		253530 RALA_HUMAN (4-169): 5.37e-58: 182: 53.29		CAPON_HUMAN (68-316): 6.44e-39: 151: 19.05
+	Hs
		203195 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SYNJ1_HUMAN (217-607): 6.26e-12: 70.9: 11.21