HitPredict

Interactor 1: RAS2 (P01120)
Ras-like protein 2 (EC 3.6.5.2)
Gene: RAS2

Interactor 2: CDC24 (P11433)
Cell division control protein 24 (Calcium regulatory protein)
Gene: CDC24

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.826

Property	Details
Experiments	32595981, 34158474
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ras~RhoGEF
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 322 Sc			1 854
+	Sc
		350758 RAS1_YEAST (1-321): 1.11e-90: 274: 57.72		CDC24_YEAST (1-854): 0: 591: 100.00
+	Sc
		509394 RSR1_YEAST (8-277): 1.17e-84: 258: 37.00		CDC24_YEAST (1-854): 0: 591: 100.00
+	Hs
		914091 RB11A_HUMAN (4-218): 3.25e-86: 259: 27.32		ITSN1_HUMAN (103-591): 3.27e-89: 312: 17.91
+	Hs
		895058 RAB2A_HUMAN (1-216): 2.11e-77: 237: 29.49		TIAM1_HUMAN (57-781): 3.01e-85: 300: 16.47
+	Hs
		349105 RASH_HUMAN (10-172): 4.41e-58: 187: 64.42		VAV_HUMAN (135-843): 2.77e-98: 327: 13.54
+	Hs
		299226 RASK_HUMAN (10-172): 1.82e-58: 187: 64.42		FARP2_HUMAN (16-645): 1.24e-94: 321: 14.47
+	Hs
		350721 RASK_HUMAN (10-172): 1.82e-58: 187: 64.42		FARP1_HUMAN (16-644): 1.09e-94: 321: 14.24
+	Hs
		299225 RASN_HUMAN (10-190): 7.41e-58: 186: 61.54		FARP2_HUMAN (16-645): 1.24e-94: 321: 14.47
+	Hs
		349026 RASN_HUMAN (10-190): 7.41e-58: 186: 61.54		FARP1_HUMAN (16-644): 1.09e-94: 321: 14.24
+	Hs
		349312 RASH_HUMAN (10-172): 4.41e-58: 187: 64.42		RGRF1_HUMAN (171-846): 3.7e-92: 318: 11.50
+	Hs
		279852 RB11A_HUMAN (4-218): 3.25e-86: 259: 27.32		TRIO_HUMAN (173-775): 9.94e-67: 245: 14.65
+	Hs
		349341 RASH_HUMAN (10-172): 4.41e-58: 187: 64.42		ITSN1_HUMAN (103-591): 3.27e-89: 312: 17.91
+	Hs
		349422 RASH_HUMAN (10-172): 4.41e-58: 187: 64.42		FGD6_HUMAN (21-736): 1.16e-89: 312: 12.62
+	Hs
		350195 RASK_HUMAN (10-172): 1.82e-58: 187: 64.42		ITSN1_HUMAN (103-591): 3.27e-89: 312: 17.91
+	Hs
		350280 RASK_HUMAN (10-172): 1.82e-58: 187: 64.42		FGD6_HUMAN (21-736): 1.16e-89: 312: 12.62
+	Hs
		349282 RASH_HUMAN (10-172): 4.41e-58: 187: 64.42		TIAM1_HUMAN (57-781): 3.01e-85: 300: 16.47
+	Hs
		350128 RASK_HUMAN (10-172): 1.82e-58: 187: 64.42		TIAM1_HUMAN (57-781): 3.01e-85: 300: 16.47
+	Hs
		156389 RASK_HUMAN (10-172): 1.82e-58: 187: 64.42		RGRF2_HUMAN (171-771): 1.32e-85: 299: 12.31
+	Hs
		348640 RASN_HUMAN (10-190): 7.41e-58: 186: 61.54		TIAM1_HUMAN (57-781): 3.01e-85: 300: 16.47
+	Hs
		279827 RASK_HUMAN (10-172): 1.82e-58: 187: 64.42		TRIO_HUMAN (173-775): 9.94e-67: 245: 14.65