HitPredict

Interactor 1: LEF1 (P27782)
Lymphoid enhancer-binding factor 1 (LEF-1)
Gene: LEF1

Interactor 2: TF7L2 (Q924A0)
Transcription factor 7-like 2 (HMG box transcription factor 4) (T-cell-specific transcription factor 4) (T-cell factor 4) (TCF-4) (mTCF-4)
Gene: Tcf7l2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24748645
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HMG_box~HMG_box
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003682 - chromatin binding
and 14 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 397
Mm

1 459
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024