Interactor 1: PDGFB (P01127)
Platelet-derived growth factor subunit B (PDGF subunit B) (PDGF-2) (Platelet-derived growth factor B chain) (Platelet-derived growth factor beta polypeptide) (Proto-oncogene c-Sis) (Becaplermin)
Gene: PDGFB

Interactor 2: PDGFB (P01127)
Platelet-derived growth factor subunit B (PDGF subunit B) (PDGF-2) (Platelet-derived growth factor B chain) (Platelet-derived growth factor beta polypeptide) (Proto-oncogene c-Sis) (Becaplermin)
Gene: PDGFB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.849

The method score is based on:

Property Details
Experiments 1396586, 23139410, 7679113
Identification Methods x-ray crystallography, electrophoretic mobility-based method
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PDGF~PDGF, PDGF~PDGF_N
Common GO terms GO:0000139 - Golgi membrane
GO:0001892 - embryonic placenta development
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0002548 - monocyte chemotaxis
GO:0003104 - positive regulation of glomerular filtration
and 68 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 241
Hs

1 241
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024