HitPredict

Interactor 1: LDLR (P01130)
Low-density lipoprotein receptor (LDL receptor)
Gene: LDLR

Interactor 2: PRG2 (P13727)
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
Gene: PRG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 860 Hs			1 222
+	Hs
		351116 LDLR_HUMAN (1-860): 0: 697: 100.00		PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30
+	Hs
		270257 LRP6_HUMAN (194-374): 7.63e-12: 71.8: 26.60		PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00
+	Hs
		258290 LRP5_HUMAN (195-364): 1.29e-10: 67.5: 26.14		PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00
+	Hs
		533026 SORL_HUMAN (17-104): 1.75e-09: 63.9: 43.33		PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00
+	Hs
		270349 LRP6_HUMAN (194-374): 7.63e-12: 71.8: 26.60		PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30