HitPredict

Interactor 1: EGF (P01132)
Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor]
Gene: EGF

Interactor 2: EGFR (Q01279)
Epidermal growth factor receptor (EC 2.7.10.1)
Gene: EGFR

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 8702666, 2022652
Identification Methods cross-linking study, biochemical
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF~Furin-like, EGF~Recep_L_domain
Common GO terms GO:0005886 - plasma membrane
GO:0007173 - epidermal growth factor receptor signaling pathway
GO:0008283 - cell population proliferation
GO:0008284 - positive regulation of cell population proliferation
GO:0030297 - transmembrane receptor protein tyrosine kinase activator activity
and 10 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1217
Mm

1 1210
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024