HitPredict

Interactor 1: PRL (P01236)
Prolactin (PRL)
Gene: PRL

Interactor 2: PRLR (P16471)
Prolactin receptor (PRL-R)
Gene: PRLR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.825

The method score is based on:

Property Details
Experiments 22325776, 23048206
Identification Methods circular dichroism, nuclear magnetic resonance, anti bait coimmunoprecipitation, proximity ligation assay
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EpoR_lig-bind~Hormone_1
Common GO terms GO:0005576 - extracellular region
GO:0007595 - lactation
GO:0008284 - positive regulation of cell population proliferation
GO:0031904 - endosome lumen
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 227
Hs

1 622
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024