Protein: DPOLL
DNA polymerase lambda (Pol Lambda) (EC 2.7.7.7) (EC 4.2.99.-) (DNA polymerase beta-2) (Pol beta2) (DNA polymerase kappa)

Gene: DPOLL, POLL
Organism: Homo sapiens
Interactions: 74
UniProt ID: Q9UGP5

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0003677 - DNA binding
GO:0003887 - DNA-directed DNA polymerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

848979

MAGAC
Melanoma-associated antigen 12

3

1

High-throughput

0.675

High

391101

TRFL
Lactotransferrin

3

1

High-throughput

0.656

High

407904

SEMG1
Semenogelin-1

3

3

High-throughput

0.656

High

1036600

SEMG2
Semenogelin-2

3

3

High-throughput

0.656

High

1151306

MED1
Mediator of RNA polymerase II transcription subunit 1

3

1

High-throughput

0.656

High

1307397

RIOX2
Ribosomal oxygenase 2

3

1

High-throughput

0.656

High

1459622

NOSIP
Nitric oxide synthase-interacting protein

3

1

High-throughput

0.656

High

551319

PCNA
Proliferating cell nuclear antigen

3

4

Small-scale

0.655

High

668063

CDK2
Cyclin-dependent kinase 2

2

1

Small-scale

0.629

High

617751

XRCC1
DNA repair protein XRCC1

1

1

Small-scale

0.618

High

476412

K1C16
Keratin, type I cytoskeletal 16

2

2

High-throughput

0.606

High

659623

CRCM
Colorectal mutant cancer protein

2

2

High-throughput

0.606

High

848218

MAGA2
Melanoma-associated antigen 2

2

1

High-throughput

0.606

High

1459193

ZRAN1
Ubiquitin thioesterase ZRANB1

2

1

High-throughput

0.606

High

1317015

FAM9B
Protein FAM9B

2

0

High-throughput

0.601

High

1458232

TFP11
Tuftelin-interacting protein 11

2

0

High-throughput

0.601

High

132947

ST1C2
Sulfotransferase 1C2

3

1

High-throughput

0.599

High

370123

CYTS
Cystatin-S

3

1

High-throughput

0.599

High

1213610

QNG1
Queuosine 5'-phosphate N-glycosylase/hydrolase

3

1

High-throughput

0.599

High

1368257

SYN2
Synapsin-2

3

1

High-throughput

0.599

High

1429190

LACRT
Extracellular glycoprotein lacritin

3

1

High-throughput

0.599

High

343823

LDOC1
Protein LDOC1

2

0

High-throughput

0.582

High

317425

KPCD3
Serine/threonine-protein kinase D3

2

0

High-throughput

0.580

High

332596

CCDB1
Cyclin-D1-binding protein 1

2

0

High-throughput

0.580

High

1238140

HMBX1
Homeobox-containing protein 1

2

0

High-throughput

0.580

High

1407123

MDFI
MyoD family inhibitor

2

0

High-throughput

0.580

High

1448384

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

423396

A4
Amyloid-beta precursor protein

2

0

High-throughput

0.577

High

1086342

TFCP2
Alpha-globin transcription factor CP2

1

1

High-throughput

0.573

High

1008391

PRKDC
DNA-dependent protein kinase catalytic subunit

1

2

Small-scale

0.561

High

874882

SPB4
Serpin B4

2

1

High-throughput

0.558

High

51511

FSD2
Fibronectin type III and SPRY domain-containing protein 2

1

0

High-throughput

0.557

High

475716

K1C19
Keratin, type I cytoskeletal 19

2

2

High-throughput

0.553

High

1277650

K1C27
Keratin, type I cytoskeletal 27

2

2

High-throughput

0.553

High

783444

TRI23
E3 ubiquitin-protein ligase TRIM23

1

0

High-throughput

0.549

High

1459621

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.549

High

554856

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

1

High-throughput

0.536

High

642115

ODBB
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

1

1

High-throughput

0.536

High

1065479

SSRP1
FACT complex subunit SSRP1

1

2

High-throughput

0.536

High

1122963

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

1

1

High-throughput

0.536

High

1459623

SP16H
FACT complex subunit SPT16

1

1

High-throughput

0.536

High

351742

SG1D1
Secretoglobin family 1D member 1

2

1

High-throughput

0.533

High

950429

KR107
Keratin-associated protein 10-7

1

1

High-throughput

0.523

High

1230299

K1C40
Keratin, type I cytoskeletal 40

1

2

High-throughput

0.523

High

1336494

PNMA1
Paraneoplastic antigen Ma1

1

2

High-throughput

0.523

High

1163266

H2B2E
Histone H2B type 2-E

1

5

High-throughput

0.515

High

1408064

H2B1L
Histone H2B type 1-L

1

4

High-throughput

0.515

High

451710

PGK2
Phosphoglycerate kinase 2

1

0

High-throughput

0.513

High

589958

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.513

High

696780

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.513

High

769432

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.513

High

1369661

DNSL2
Deoxyribonuclease-1-like 2

1

0

High-throughput

0.513

High

1391971

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.513

High

1449536

INKA2
PAK4-inhibitor INKA2

1

0

High-throughput

0.513

High

1459620

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

0

High-throughput

0.513

High

443547

CDK1
Cyclin-dependent kinase 1

1

1

Small-scale

0.501

High

906814

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

7

Small-scale

0.501

High

909406

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

7

Small-scale

0.501

High

957227

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

7

Small-scale

0.501

High

971242

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

9

Small-scale

0.501

High

982354

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

7

Small-scale

0.501

High

1102288

ATM
Serine-protein kinase ATM

1

2

Small-scale

0.501

High

1280572

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

Small-scale

0.501

High

1459619

MUTYH
Adenine DNA glycosylase

1

0

Small-scale

0.480

High

559535

XRCC5
X-ray repair cross-complementing protein 5

1

1

Small-scale

0.479

High

508781

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

Small-scale

0.458

High

635398

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

0

High-throughput

0.458

High

950030

KR103
Keratin-associated protein 10-3

1

1

High-throughput

0.439

High

65184

GG6L9
Golgin subfamily A member 6-like protein 9

2

0

High-throughput

0.316

High

1009740

NGAL
Neutrophil gelatinase-associated lipocalin

2

0

High-throughput

0.316

High

1380455

MAL2
Protein MAL2

2

0

High-throughput

0.316

High

1388214

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

2

0

High-throughput

0.316

High

1458523

TR10D
Tumor necrosis factor receptor superfamily member 10D

2

0

High-throughput

0.316

High

1322292

CLYBL
Citramalyl-CoA lyase, mitochondrial

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025