HitPredict - High confidence protein-protein interactions

Interactor 1: INS (P01315)
Insulin [Cleaved into: Insulin B chain; Insulin A chain]
Gene: INS

Interactor 2: INS (P01315)
Insulin [Cleaved into: Insulin B chain; Insulin A chain]
Gene: INS

Species: Sus scrofa

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.786

Property	Details
Experiments	23416304, 7492558
Identification Methods	atomic force microscopy, circular dichroism, x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Insulin~Insulin
Common GO terms	GO:0005158 - insulin receptor binding GO:0005159 - insulin-like growth factor receptor binding GO:0005179 - hormone activity GO:0005615 - extracellular space GO:0006006 - glucose metabolic process and 16 others more... GO:0008286 - insulin receptor signaling pathway GO:0008610 - lipid biosynthetic process GO:0009101 - glycoprotein biosynthetic process GO:0010907 - positive regulation of glucose metabolic process GO:0019249 - lactate biosynthetic process GO:0030335 - positive regulation of cell migration GO:0031954 - positive regulation of protein autophosphorylation GO:0042158 - lipoprotein biosynthetic process GO:0042593 - glucose homeostasis GO:0045721 - negative regulation of gluconeogenesis GO:0045723 - positive regulation of fatty acid biosynthetic process GO:0045740 - positive regulation of DNA replication GO:0046628 - positive regulation of insulin receptor signaling pathway GO:0050714 - positive regulation of protein secretion GO:0051006 - positive regulation of lipoprotein lipase activity GO:1903576 - response to L-arginine
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	108
Ss

1	108

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Last updated: 15 Jul 2024