Protein: STX1A
Syntaxin-1A (Neuron-specific antigen HPC-1)

Gene: STX1A
Organism: Homo sapiens
Interactions: 176
UniProt ID: Q16623

Gene Ontology (top 5):
GO:0000149 - SNARE binding
GO:0001956 - positive regulation of neurotransmitter secretion
GO:0005484 - SNAP receptor activity
GO:0005576 - extracellular region
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

926213

VAMP2
Vesicle-associated membrane protein 2

10

20

Small-scale

0.971

High

901790

STXB1
Syntaxin-binding protein 1

9

20

Small-scale

0.963

High

1083928

STX1A
Syntaxin-1A

5

18

Small-scale

0.924

High

1083986

SNAB
Beta-soluble NSF attachment protein

3

20

High-throughput

0.861

High

263248

SC22B
Vesicle-trafficking protein SEC22b

3

20

Small-scale

0.853

High

306800

VAMP5
Vesicle-associated membrane protein 5

3

20

High-throughput

0.845

High

620271

VAMP1
Vesicle-associated membrane protein 1

3

20

Small-scale

0.845

High

156112

CPLX1
Complexin-1

3

2

Small-scale

0.827

High

1083970

SYTL4
Synaptotagmin-like protein 4

2

11

Small-scale

0.806

High

1083961

STXB6
Syntaxin-binding protein 6

2

4

High-throughput

0.789

High

151576

GOSR2
Golgi SNAP receptor complex member 2

2

20

High-throughput

0.783

High

152159

STX16
Syntaxin-16

2

17

High-throughput

0.783

High

178555

STX7
Syntaxin-7

2

18

High-throughput

0.783

High

212845

STX6
Syntaxin-6

2

20

High-throughput

0.783

High

235176

STX10
Syntaxin-10

2

20

High-throughput

0.783

High

261664

VAMP4
Vesicle-associated membrane protein 4

2

20

High-throughput

0.783

High

269423

STX11
Syntaxin-11

2

18

High-throughput

0.783

High

699264

STX2
Syntaxin-2

2

19

High-throughput

0.783

High

1017646

STX4
Syntaxin-4

2

17

High-throughput

0.783

High

1027472

STX5
Syntaxin-5

2

20

High-throughput

0.783

High

1030146

STX3
Syntaxin-3

2

18

High-throughput

0.783

High

1079327

VAMP3
Vesicle-associated membrane protein 3

2

20

High-throughput

0.783

High

1083946

STX12
Syntaxin-12

2

18

High-throughput

0.783

High

1084006

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

2

20

High-throughput

0.783

High

1084012

STX8
Syntaxin-8

2

20

High-throughput

0.783

High

599575

SYT1
Synaptotagmin-1

2

8

Small-scale

0.778

High

873547

SNAA
Alpha-soluble NSF attachment protein

2

20

Small-scale

0.768

High

893278

SNP25
Synaptosomal-associated protein 25

14

20

Small-scale

0.760

High

118037

SNP23
Synaptosomal-associated protein 23

7

20

Small-scale

0.743

High

1083981

VAMP8
Vesicle-associated membrane protein 8

1

20

Small-scale

0.724

High

770596

TXLNA
Alpha-taxilin

4

8

Small-scale

0.696

High

320326

SNP29
Synaptosomal-associated protein 29

4

20

Small-scale

0.688

High

674588

SC6A1
Sodium- and chloride-dependent GABA transporter 1

3

15

Small-scale

0.667

High

118326

HAX1
HCLS1-associated protein X-1

3

1

High-throughput

0.656

High

1083930

DGUOK
Deoxyguanosine kinase, mitochondrial

3

1

High-throughput

0.656

High

1083997

KTU
Protein kintoun

3

1

High-throughput

0.656

High

850569

VAMP7
Vesicle-associated membrane protein 7

1

20

Small-scale

0.647

High

529182

CFTR
Cystic fibrosis transmembrane conductance regulator

2

1

Small-scale

0.624

High

968115

SC6A3
Sodium-dependent dopamine transporter

2

15

Small-scale

0.624

High

155797

UN13B
Protein unc-13 homolog B

1

6

Small-scale

0.621

High

1083979

TSNA1
t-SNARE domain-containing protein 1

1

19

High-throughput

0.621

High

1083940

CPLX2
Complexin-2

1

2

Small-scale

0.618

High

169475

BET1
BET1 homolog

2

20

High-throughput

0.606

High

309215

APOL3
Apolipoprotein L3

2

2

High-throughput

0.606

High

452234

HMOX1
Heme oxygenase 1

2

2

High-throughput

0.606

High

673323

MIP
Lens fiber major intrinsic protein

2

16

High-throughput

0.606

High

838858

EMD
Emerin

2

2

High-throughput

0.606

High

887864

CD81
CD81 antigen

2

11

High-throughput

0.606

High

888254

MYPR
Myelin proteolipid protein

2

4

High-throughput

0.606

High

1021906

SEC20
Vesicle transport protein SEC20

2

6

High-throughput

0.606

High

1022707

MALL
MAL-like protein

2

2

High-throughput

0.606

High

1036384

GPM6B
Neuronal membrane glycoprotein M6-b

2

4

High-throughput

0.606

High

1083931

AR13B
ADP-ribosylation factor-like protein 13B

2

14

High-throughput

0.606

High

1083935

RTP2
Receptor-transporting protein 2

2

1

High-throughput

0.606

High

1083936

SNP47
Synaptosomal-associated protein 47

2

5

High-throughput

0.606

High

1083938

PLPP4
Phospholipid phosphatase 4

2

5

High-throughput

0.606

High

1083953

EMC5
ER membrane protein complex subunit 5

2

3

High-throughput

0.606

High

1083954

TM199
Transmembrane protein 199

2

2

High-throughput

0.606

High

1083955

JAGN1
Protein jagunal homolog 1

2

2

High-throughput

0.606

High

1083960

CLC1A
C-type lectin domain family 1 member A

2

1

High-throughput

0.606

High

1083965

BT2A2
Butyrophilin subfamily 2 member A2

2

1

High-throughput

0.606

High

1083968

AQP3
Aquaporin-3

2

11

High-throughput

0.606

High

1083969

FAM3C
Protein FAM3C

2

1

High-throughput

0.606

High

1083976

SC22A
Vesicle-trafficking protein SEC22a

2

20

High-throughput

0.606

High

1083978

RMD2
Regulator of microtubule dynamics protein 2

2

2

High-throughput

0.606

High

1083980

APOL2
Apolipoprotein L2

2

2

High-throughput

0.606

High

1083983

TACAN
Ion channel TACAN

2

2

High-throughput

0.606

High

1084000

USE1
Vesicle transport protein USE1

2

6

High-throughput

0.606

High

1084001

NINJ2
Ninjurin-2

2

1

High-throughput

0.606

High

1084010

BL1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6

2

2

High-throughput

0.606

High

1084013

T3JAM
TRAF3-interacting JNK-activating modulator

2

7

High-throughput

0.606

High

1084017

SERP1
Stress-associated endoplasmic reticulum protein 1

2

3

High-throughput

0.606

High

1083937

STXB5
Syntaxin-binding protein 5

2

16

Small-scale

0.602

High

1084008

NUFP1
FMR1-interacting protein NUFIP1

3

1

High-throughput

0.599

High

310656

VAPB
Vesicle-associated membrane protein-associated protein B/C

2

20

Small-scale

0.595

High

681224

SC6A4
Sodium-dependent serotonin transporter

2

15

Small-scale

0.595

High

1058634

KCNB1
Potassium voltage-gated channel subfamily B member 1

2

2

Small-scale

0.595

High

47978

A0AVG3
t-SNARE domain containing 1

1

16

High-throughput

0.594

High

70807

SMIM1
Small integral membrane protein 1

2

0

High-throughput

0.580

High

352629

TNFA
Tumor necrosis factor

2

0

High-throughput

0.580

High

870013

LIPR1
Inactive pancreatic lipase-related protein 1

2

0

High-throughput

0.580

High

1082786

CDC37
Hsp90 co-chaperone Cdc37

2

0

High-throughput

0.580

High

1083819

NKG7
Protein NKG7

2

0

High-throughput

0.580

High

1083929

AOC3
Amine oxidase [copper-containing] 3

2

0

High-throughput

0.580

High

1083941

ATRAP
Type-1 angiotensin II receptor-associated protein

2

0

High-throughput

0.580

High

1083942

SNORC
Protein SNORC

2

0

High-throughput

0.580

High

1083947

VSTM4
V-set and transmembrane domain-containing protein 4 [Cleaved into: Peptide Lv]

2

0

High-throughput

0.580

High

1083948

NRM
Nurim

2

0

High-throughput

0.580

High

1083949

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

2

0

High-throughput

0.580

High

1083964

R3GEF
Guanine nucleotide exchange factor for Rab-3A

2

0

High-throughput

0.580

High

1083995

TM100
Transmembrane protein 100

2

0

High-throughput

0.580

High

1083996

EKI2
Ethanolamine kinase 2

2

0

High-throughput

0.580

High

1083998

AIG1
Androgen-induced gene 1 protein

2

0

High-throughput

0.580

High

1083952

TXLNB
Beta-taxilin

2

13

Small-scale

0.565

High

256266

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

2

Small-scale

0.561

High

845989

SCNNG
Amiloride-sensitive sodium channel subunit gamma

1

3

Small-scale

0.561

High

967561

CDR2
Cerebellar degeneration-related protein 2

2

2

High-throughput

0.558

High

66662

ZN785
Zinc finger protein 785

2

6

High-throughput

0.553

High

132485

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

2

2

High-throughput

0.553

High

196784

CYB5B
Cytochrome b5 type B

2

1

High-throughput

0.553

High

276316

UPK1B
Uroplakin-1b

2

12

High-throughput

0.553

High

305466

ZFPL1
Zinc finger protein-like 1

2

3

High-throughput

0.553

High

474052

UBFL1
Upstream-binding factor 1-like protein 1

2

1

High-throughput

0.553

High

549168

ZN250
Zinc finger protein 250

2

2

High-throughput

0.553

High

596888

MAL
Myelin and lymphocyte protein

2

2

High-throughput

0.553

High

644396

PPLA
Cardiac phospholamban

2

1

High-throughput

0.553

High

855867

ZN136
Zinc finger protein 136

2

5

High-throughput

0.553

High

940962

RNF4
E3 ubiquitin-protein ligase RNF4

2

7

High-throughput

0.553

High

1083932

T10IP
Testis-specific protein 10-interacting protein

2

1

High-throughput

0.553

High

1083933

AARD
Alanine and arginine-rich domain-containing protein

2

1

High-throughput

0.553

High

1083945

ANR46
Ankyrin repeat domain-containing protein 46

2

17

High-throughput

0.553

High

1083950

ZN440
Zinc finger protein 440

2

5

High-throughput

0.553

High

1083956

SERP2
Stress-associated endoplasmic reticulum protein 2

2

3

High-throughput

0.553

High

1083957

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

2

High-throughput

0.553

High

1083958

ZN441
Zinc finger protein 441

2

1

High-throughput

0.553

High

1083959

ZN557
Zinc finger protein 557

2

4

High-throughput

0.553

High

1083967

GIMA1
GTPase IMAP family member 1

2

3

High-throughput

0.553

High

1083971

ZN707
Zinc finger protein 707

2

5

High-throughput

0.553

High

1083973

GIMA5
GTPase IMAP family member 5

2

3

High-throughput

0.553

High

1083977

ZN479
Zinc finger protein 479

2

2

High-throughput

0.553

High

1083982

KIFC3
Kinesin-like protein KIFC3

2

2

High-throughput

0.553

High

1083992

ZN696
Zinc finger protein 696

2

4

High-throughput

0.553

High

1084003

TM14C
Transmembrane protein 14C

2

2

High-throughput

0.553

High

1084005

ABI3
ABI gene family member 3

2

9

High-throughput

0.553

High

1084011

ZN490
Zinc finger protein 490

2

6

High-throughput

0.553

High

1084014

ZN835
Zinc finger protein 835

2

3

High-throughput

0.553

High

1084016

DDX49
Probable ATP-dependent RNA helicase DDX49

2

1

High-throughput

0.553

High

443541

VIME
Vimentin

1

1

High-throughput

0.541

High

637899

PSA3
Proteasome subunit alpha type-3

1

3

High-throughput

0.541

High

1083943

DPP8
Dipeptidyl peptidase 8

1

2

High-throughput

0.515

High

1083944

Q7KZS0
SUMO-conjugating enzyme UBC9

1

6

High-throughput

0.515

High

547334

VATB1
V-type proton ATPase subunit B, kidney isoform

1

2

Small-scale

0.501

High

960288

CDK5
Cyclin-dependent kinase 5

1

2

Small-scale

0.501

High

1083987

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

3

Small-scale

0.501

High

1083988

VPS11
Vacuolar protein sorting-associated protein 11 homolog

1

13

Small-scale

0.501

High

1084004

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

13

Small-scale

0.501

High

742324

SYUA
Alpha-synuclein

1

1

Small-scale

0.500

High

930242

UBC9
SUMO-conjugating enzyme UBC9

1

6

High-throughput

0.481

High

1043827

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.481

High

621435

SC6A2
Sodium-dependent noradrenaline transporter

1

15

Small-scale

0.479

High

739593

SCNNA
Amiloride-sensitive sodium channel subunit alpha

1

3

Small-scale

0.479

High

816330

SC6A9
Sodium- and chloride-dependent glycine transporter 1

1

15

Small-scale

0.479

High

845974

SCNNB
Amiloride-sensitive sodium channel subunit beta

1

3

Small-scale

0.479

High

849548

GPM6A
Neuronal membrane glycoprotein M6-a

1

4

High-throughput

0.479

High

905930

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

2

High-throughput

0.479

High

1083972

CHM4C
Charged multivesicular body protein 4c

1

3

High-throughput

0.479

High

1084002

VAPA
Vesicle-associated membrane protein-associated protein A

1

20

Small-scale

0.479

High

1084015

SC6A5
Sodium- and chloride-dependent glycine transporter 2

1

15

Small-scale

0.479

High

1083989

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.460

High

439125

SYPH
Synaptophysin

1

0

Small-scale

0.458

High

962801

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

High-throughput

0.458

High

1083962

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

1083993

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.457

High

791595

HD
Huntingtin

1

7

High-throughput

0.445

High

898859

SMS
Somatostatin

1

1

Small-scale

0.445

High

102161

SUMO5
Small ubiquitin-related modifier 5

1

0

High-throughput

0.438

High

1083951

FAM9C
Protein FAM9C

1

1

High-throughput

0.437

High

204329

MS18B
Protein Mis18-beta

3

0

High-throughput

0.342

High

563254

ZNF12
Zinc finger protein 12

2

0

High-throughput

0.316

High

1083934

TM128
Transmembrane protein 128

2

0

High-throughput

0.316

High

1083963

TM254
Transmembrane protein 254

2

0

High-throughput

0.316

High

1083966

CD003
Uncharacterized protein C4orf3

2

0

High-throughput

0.316

High

1083974

CKLF7
CKLF-like MARVEL transmembrane domain-containing protein 7

2

0

High-throughput

0.316

High

1083975

TM41A
Transmembrane protein 41A

2

0

High-throughput

0.316

High

1083984

SMIM3
Small integral membrane protein 3

2

0

High-throughput

0.316

High

1083985

TM222
Transmembrane protein 222

2

0

High-throughput

0.316

High

1083990

TMM60
Transmembrane protein 60

2

0

High-throughput

0.316

High

1083999

CLN6
Ceroid-lipofuscinosis neuronal protein 6

2

0

High-throughput

0.316

High

1084007

PGAP2
Post-GPI attachment to proteins factor 2

2

0

High-throughput

0.316

High

1084009

ERG28
Ergosterol biosynthetic protein 28 homolog

2

0

High-throughput

0.316

High

152828

TRDMT
tRNA

1

0

High-throughput

0.282

High

1083991

CCSE2
Serine-rich coiled-coil domain-containing protein 2

1

0

High-throughput

0.282

High

483855

DWORF
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF

1

0

High-throughput

0.268

Low

1083939

GOLM2
Protein GOLM2

1

0

High-throughput

0.251

Low

1083994

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

1

0

High-throughput

0.251

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024