Protein: TOP3B
DNA topoisomerase 3-beta-1 (EC 5.6.2.1) (DNA topoisomerase III beta-1)

Gene: TOP3B
Organism: Homo sapiens
Interactions: 399
UniProt ID: O95985

Gene Ontology (top 5):
GO:0000793 - condensed chromosome
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0003916 - DNA topoisomerase activity
GO:0003917 - DNA topoisomerase type I (single strand cut, ATP-independent) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

352551

TDRD3
Tudor domain-containing protein 3

8

4

Small-scale

0.973

High

141253

DDX3X
ATP-dependent RNA helicase DDX3X

2

1

High-throughput

0.754

High

302725

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

4

2

High-throughput

0.696

High

352554

RMI1
RecQ-mediated genome instability protein 1

1

5

High-throughput

0.691

High

352367

FXR1
RNA-binding protein FXR1

4

6

High-throughput

0.676

High

352278

TOP3B
DNA topoisomerase 3-beta-1

1

1

High-throughput

0.665

High

352433

UBP2L
Ubiquitin-associated protein 2-like

3

3

High-throughput

0.640

High

352472

SND1
Staphylococcal nuclease domain-containing protein 1

3

1

Small-scale

0.640

High

352586

TRIM1
Probable E3 ubiquitin-protein ligase MID2

4

2

High-throughput

0.637

High

352524

MMS19
MMS19 nucleotide excision repair protein homolog

3

0

High-throughput

0.622

High

316240

RECQ5
ATP-dependent DNA helicase Q5

1

10

Small-scale

0.618

High

352325

DDX6
Probable ATP-dependent RNA helicase DDX6

1

2

High-throughput

0.618

High

352382

IF4A1
Eukaryotic initiation factor 4A-I

1

2

High-throughput

0.618

High

352414

DHX9
ATP-dependent RNA helicase A

1

2

Small-scale

0.618

High

352430

DX39B
Spliceosome RNA helicase DDX39B

1

2

High-throughput

0.618

High

352434

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

1

11

High-throughput

0.618

High

352435

IF4A2
Eukaryotic initiation factor 4A-II

1

3

High-throughput

0.618

High

352466

DHX57
Putative ATP-dependent RNA helicase DHX57

1

2

High-throughput

0.618

High

352473

DHX30
ATP-dependent RNA helicase DHX30

1

2

High-throughput

0.618

High

352564

DDX28
Probable ATP-dependent RNA helicase DDX28

1

2

High-throughput

0.618

High

352582

DDX20
Probable ATP-dependent RNA helicase DDX20

1

4

High-throughput

0.618

High

352597

DD19B
ATP-dependent RNA helicase DDX19B

1

3

High-throughput

0.618

High

352328

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

1

High-throughput

0.611

High

352497

THOC2
THO complex subunit 2

2

1

High-throughput

0.611

High

352549

CIA2A
Cytosolic iron-sulfur assembly component 2A

2

1

High-throughput

0.611

High

352602

ADIP
Afadin- and alpha-actinin-binding protein

2

0

High-throughput

0.601

High

352286

P53
Cellular tumor antigen p53

2

1

High-throughput

0.601

High

352368

FXR2
RNA-binding protein FXR2

2

6

High-throughput

0.601

High

352412

FMR1
Fragile X messenger ribonucleoprotein 1

2

6

High-throughput

0.601

High

352478

YTHD3
YTH domain-containing family protein 3

2

2

High-throughput

0.601

High

352542

YTHD1
YTH domain-containing family protein 1

2

2

High-throughput

0.601

High

352609

CIA2B
Cytosolic iron-sulfur assembly component 2B

2

1

High-throughput

0.601

High

352618

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

2

3

High-throughput

0.601

High

352560

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

0

Small-scale

0.589

High

352541

PDIP3
Polymerase delta-interacting protein 3

2

0

High-throughput

0.585

High

352399

VIGLN
Vigilin

2

4

High-throughput

0.584

High

352417

GRSF1
G-rich sequence factor 1

2

2

High-throughput

0.584

High

352426

G3BP1
Ras GTPase-activating protein-binding protein 1

2

3

High-throughput

0.584

High

352471

LARP4
La-related protein 4

2

1

High-throughput

0.584

High

352486

Z3H7A
Zinc finger CCCH domain-containing protein 7A

2

1

High-throughput

0.584

High

352505

LAR4B
La-related protein 4B

2

1

High-throughput

0.584

High

352517

FUBP3
Far upstream element-binding protein 3

2

3

High-throughput

0.584

High

352526

ATX2
Ataxin-2

2

1

High-throughput

0.584

High

352543

UNK
RING finger protein unkempt homolog

2

1

High-throughput

0.584

High

352572

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

2

1

High-throughput

0.584

High

352614

YTHD2
YTH domain-containing family protein 2

2

2

High-throughput

0.584

High

352315

ZN250
Zinc finger protein 250

2

0

High-throughput

0.580

High

352437

FASTK
Fas-activated serine/threonine kinase

2

0

High-throughput

0.580

High

352467

GASP3
G protein-coupled receptor associated sorting protein 3

2

0

High-throughput

0.580

High

352605

AXIN2
Axin-2

2

0

High-throughput

0.580

High

274067

ANR17
Ankyrin repeat domain-containing protein 17

2

0

High-throughput

0.559

High

345228

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

0

High-throughput

0.559

High

352357

IQGA1
Ras GTPase-activating-like protein IQGAP1

2

0

Small-scale

0.559

High

352431

BYST
Bystin

2

0

High-throughput

0.559

High

352442

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

2

0

High-throughput

0.559

High

352583

CNOT7
CCR4-NOT transcription complex subunit 7

2

0

High-throughput

0.559

High

352600

TNR6B
Trinucleotide repeat-containing gene 6B protein

2

0

High-throughput

0.559

High

207778

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

2

1

High-throughput

0.558

High

352307

ACTN1
Alpha-actinin-1

2

3

High-throughput

0.558

High

352464

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

1

High-throughput

0.553

High

137407

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

1

1

High-throughput

0.536

High

162420

ANM5
Protein arginine N-methyltransferase 5

1

1

High-throughput

0.536

High

163886

NDC80
Kinetochore protein NDC80 homolog

1

1

High-throughput

0.536

High

277499

H2AY
Core histone macro-H2A.1

1

1

High-throughput

0.536

High

352290

HMGN2
Non-histone chromosomal protein HMG-17

1

1

High-throughput

0.536

High

352292

H2B1J
Histone H2B type 1-J

1

2

High-throughput

0.536

High

352320

RCC1
Regulator of chromosome condensation

1

2

High-throughput

0.536

High

352353

NOP2
28S rRNA

1

1

High-throughput

0.536

High

352379

H2B1D
Histone H2B type 1-D

1

2

High-throughput

0.536

High

352394

H31
Histone H3.1

1

2

High-throughput

0.536

High

352397

H33
Histone H3.3

1

2

High-throughput

0.536

High

352507

RBP56
TATA-binding protein-associated factor 2N

1

1

High-throughput

0.536

High

352513

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

2

High-throughput

0.536

High

352525

TSNAX
Translin-associated protein X

1

1

High-throughput

0.536

High

352606

TDRKH
Tudor and KH domain-containing protein

1

4

High-throughput

0.536

High

352607

RBMX2
RNA-binding motif protein, X-linked 2

1

2

High-throughput

0.536

High

352484

MIB1
E3 ubiquitin-protein ligase MIB1

2

2

Small-scale

0.533

High

352576

IBTK
Inhibitor of Bruton tyrosine kinase

2

2

High-throughput

0.533

High

352370

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

2

High-throughput

0.515

High

352384

ARP3
Actin-related protein 3

1

1

High-throughput

0.515

High

352385

ARP2
Actin-related protein 2

1

1

High-throughput

0.515

High

352405

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

1

High-throughput

0.515

High

352419

AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

1

1

High-throughput

0.515

High

352444

SYK
Lysine--tRNA ligase

1

1

High-throughput

0.515

High

352447

SAFB1
Scaffold attachment factor B1

1

2

High-throughput

0.515

High

352499

IPO4
Importin-4

1

1

High-throughput

0.515

High

352520

RBM14
RNA-binding protein 14

1

1

High-throughput

0.515

High

352596

MYO6
Unconventional myosin-VI

1

1

High-throughput

0.515

High

352598

G3BP2
Ras GTPase-activating protein-binding protein 2

1

4

High-throughput

0.515

High

228138

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.513

High

273386

KDM4A
Lysine-specific demethylase 4A

1

0

High-throughput

0.513

High

283002

PSIP1
PC4 and SFRS1-interacting protein

1

0

High-throughput

0.513

High

303370

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.513

High

352289

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.513

High

352327

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

352340

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.513

High

352344

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

352352

CBX5
Chromobox protein homolog 5

1

0

High-throughput

0.513

High

352355

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

352373

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.513

High

352387

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

352407

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

0

High-throughput

0.513

High

352485

H2A2B
Histone H2A type 2-B

1

0

High-throughput

0.513

High

352515

THOC1
THO complex subunit 1

1

0

High-throughput

0.513

High

352568

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.513

High

352555

ZN408
Zinc finger protein 408

1

1

High-throughput

0.508

High

352378

EPIPL
Epiplakin

1

0

High-throughput

0.493

High

352380

ARPC4
Actin-related protein 2/3 complex subunit 4

1

0

High-throughput

0.493

High

352313

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

1

Small-scale

0.481

High

352364

CENPF
Centromere protein F

1

2

Small-scale

0.481

High

47942

RBM47
RNA-binding protein 47

1

2

High-throughput

0.479

High

124877

GTPB1
GTP-binding protein 1

1

1

High-throughput

0.479

High

133911

IPO5
Importin-5

1

1

High-throughput

0.479

High

159454

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

2

High-throughput

0.479

High

177983

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

1

High-throughput

0.479

High

213446

CTIF
CBP80/20-dependent translation initiation factor

1

1

High-throughput

0.479

High

224570

ACTN4
Alpha-actinin-4

1

3

High-throughput

0.479

High

250392

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

2

High-throughput

0.479

High

352296

LYN
Tyrosine-protein kinase Lyn

1

1

High-throughput

0.479

High

352297

RHOC
Rho-related GTP-binding protein RhoC

1

1

High-throughput

0.479

High

352298

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

352300

SNRPA
U1 small nuclear ribonucleoprotein A

1

2

High-throughput

0.479

High

352306

PABP1
Polyadenylate-binding protein 1

1

1

High-throughput

0.479

High

352308

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.479

High

352309

XRCC5
X-ray repair cross-complementing protein 5

1

1

High-throughput

0.479

High

352312

ENPL
Endoplasmin

1

1

High-throughput

0.479

High

352314

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

352316

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

352321

MSH3
DNA mismatch repair protein Msh3

1

1

High-throughput

0.479

High

352322

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

2

High-throughput

0.479

High

352326

TTP
mRNA decay activator protein ZFP36

1

1

High-throughput

0.479

High

352331

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

2

High-throughput

0.479

High

352335

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

1

High-throughput

0.479

High

352336

DNJA1
DnaJ homolog subfamily A member 1

1

1

High-throughput

0.479

High

352339

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

352343

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.479

High

352345

RL13A
Large ribosomal subunit protein uL13

1

2

High-throughput

0.479

High

352351

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

2

High-throughput

0.479

High

352354

CRKL
Crk-like protein

1

3

High-throughput

0.479

High

352361

PRC2A
Protein PRRC2A

1

2

High-throughput

0.479

High

352366

DNLI3
DNA ligase 3

1

1

High-throughput

0.479

High

352369

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2

1

3

High-throughput

0.479

High

352371

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

1

High-throughput

0.479

High

352372

PLK1
Serine/threonine-protein kinase PLK1

1

2

High-throughput

0.479

High

352375

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

352377

RBM11
Splicing regulator RBM11

1

4

High-throughput

0.479

High

352383

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

352386

RHOA
Transforming protein RhoA

1

1

High-throughput

0.479

High

352392

YBOX1
Y-box-binding protein 1

1

1

Small-scale

0.479

High

352406

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.479

High

352408

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

1

1

High-throughput

0.479

High

352411

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

3

High-throughput

0.479

High

352418

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

352423

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

2

High-throughput

0.479

High

352424

ROA0
Heterogeneous nuclear ribonucleoprotein A0

1

2

High-throughput

0.479

High

352425

SRSF9
Serine/arginine-rich splicing factor 9

1

1

High-throughput

0.479

High

352432

SAFB2
Scaffold attachment factor B2

1

2

High-throughput

0.479

High

352436

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

1

High-throughput

0.479

High

352440

MDC1
Mediator of DNA damage checkpoint protein 1

1

2

High-throughput

0.479

High

352445

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

352450

ELAV1
ELAV-like protein 1

1

1

High-throughput

0.479

High

352452

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

1

High-throughput

0.479

High

352457

PRC2B
Protein PRRC2B

1

2

High-throughput

0.479

High

352460

UBAP2
Ubiquitin-associated protein 2

1

3

High-throughput

0.479

High

352474

RIR2B
Ribonucleoside-diphosphate reductase subunit M2 B

1

1

High-throughput

0.479

High

352475

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

2

High-throughput

0.479

High

352479

PATL1
Protein PAT1 homolog 1

1

1

High-throughput

0.479

High

352480

PABP2
Polyadenylate-binding protein 2

1

2

High-throughput

0.479

High

352482

KTN1
Kinectin

1

1

High-throughput

0.479

High

352483

EST1A
Telomerase-binding protein EST1A

1

1

High-throughput

0.479

High

352488

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

1

1

High-throughput

0.479

High

352494

LS14A
Protein LSM14 homolog A

1

1

High-throughput

0.479

High

352498

WDR36
WD repeat-containing protein 36

1

2

High-throughput

0.479

High

352504

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

1

High-throughput

0.479

High

352506

ARC1A
Actin-related protein 2/3 complex subunit 1A

1

3

High-throughput

0.479

High

352508

CELF1
CUGBP Elav-like family member 1

1

2

High-throughput

0.479

High

352509

RENT1
Regulator of nonsense transcripts 1

1

3

High-throughput

0.479

High

352510

DAZL
Deleted in azoospermia-like

1

3

High-throughput

0.479

High

352514

RBM33
RNA-binding protein 33

1

2

High-throughput

0.479

High

352523

RBM15
RNA-binding protein 15

1

1

High-throughput

0.479

High

352531

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

1

High-throughput

0.479

High

352534

TRI56
E3 ubiquitin-protein ligase TRIM56

1

2

High-throughput

0.479

High

352536

AASD1
Alanyl-tRNA editing protein Aarsd1

1

2

High-throughput

0.479

High

352539

LS14B
Protein LSM14 homolog B

1

1

High-throughput

0.479

High

352545

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

1

High-throughput

0.479

High

352546

RGAP1
Rac GTPase-activating protein 1

1

2

High-throughput

0.479

High

352557

XPO5
Exportin-5

1

1

High-throughput

0.479

High

352558

RC3H2
Roquin-2

1

2

High-throughput

0.479

High

352559

MOV10
Helicase MOV-10

1

3

High-throughput

0.479

High

352567

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

1

High-throughput

0.479

High

352573

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

2

High-throughput

0.479

High

352589

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

3

High-throughput

0.479

High

352601

VDAC3
Non-selective voltage-gated ion channel VDAC3

1

2

High-throughput

0.479

High

352603

R3HD2
R3H domain-containing protein 2

1

1

High-throughput

0.479

High

352604

RT07
Small ribosomal subunit protein uS7m

1

1

High-throughput

0.479

High

352610

STRAP
Serine-threonine kinase receptor-associated protein

1

2

High-throughput

0.479

High

352617

RBM8A
RNA-binding protein 8A

1

2

High-throughput

0.479

High

123541

MYO1C
Unconventional myosin-Ic

1

2

High-throughput

0.470

High

227747

MYO1B
Unconventional myosin-Ib

1

3

High-throughput

0.470

High

270292

WDR1
WD repeat-containing protein 1

1

1

High-throughput

0.470

High

318225

MYO1D
Unconventional myosin-Id

1

2

High-throughput

0.470

High

352294

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

1

High-throughput

0.470

High

352348

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.470

High

352358

SYQ
Glutamine--tRNA ligase

1

1

High-throughput

0.470

High

352330

GRN
Progranulin

1

0

Small-scale

0.460

High

352556

RENT2
Regulator of nonsense transcripts 2

1

0

High-throughput

0.460

High

63929

CNOT1
CCR4-NOT transcription complex subunit 1

1

0

High-throughput

0.458

High

134513

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.458

High

179286

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

High-throughput

0.458

High

179435

ARPC3
Actin-related protein 2/3 complex subunit 3

1

0

High-throughput

0.458

High

183567

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.458

High

240409

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

249943

OGA
Protein O-GlcNAcase

1

0

High-throughput

0.458

High

257704

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

0

High-throughput

0.458

High

258405

EDF1
Endothelial differentiation-related factor 1

1

0

High-throughput

0.458

High

283641

GPC4
Glypican-4

1

0

High-throughput

0.458

High

285552

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.458

High

286136

CSDE1
Cold shock domain-containing protein E1

1

0

High-throughput

0.458

High

300084

GLRX3
Glutaredoxin-3

1

0

High-throughput

0.458

High

336304

SVIL
Supervillin

1

0

High-throughput

0.458

High

352285

MYCN
N-myc proto-oncogene protein

1

0

High-throughput

0.458

High

352288

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.458

High

352304

BIP
Endoplasmic reticulum chaperone BiP

1

0

Small-scale

0.458

High

352318

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.458

High

352323

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

352329

PYR1
Multifunctional protein CAD

1

0

High-throughput

0.458

High

352338

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

352341

MYH10
Myosin-10

1

0

High-throughput

0.458

High

352347

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

352356

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.458

High

352359

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

0

High-throughput

0.458

High

352360

IREB2
Iron-responsive element-binding protein 2

1

0

High-throughput

0.458

High

352362

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.458

High

352363

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.458

High

352365

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.458

High

352374

SYRC
Arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

352376

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

0

High-throughput

0.458

High

352388

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

0

High-throughput

0.458

High

352391

ACTG
Actin, cytoplasmic 2

1

0

Small-scale

0.458

High

352395

GTF2I
General transcription factor II-I

1

0

High-throughput

0.458

High

352396

PRKDC
DNA-dependent protein kinase catalytic subunit

1

0

High-throughput

0.458

High

352398

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

352400

FKBP3
Peptidyl-prolyl cis-trans isomerase FKBP3

1

0

High-throughput

0.458

High

352401

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

Small-scale

0.458

High

352402

U2AF1
Splicing factor U2AF 35 kDa subunit

1

0

High-throughput

0.458

High

352404

OTUD4
OTU domain-containing protein 4

1

0

High-throughput

0.458

High

352410

TF65
Transcription factor p65

1

0

Small-scale

0.458

High

352413

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

Small-scale

0.458

High

352415

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.458

High

352416

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.458

High

352420

FOXL1
Forkhead box protein L1

1

0

High-throughput

0.458

High

352438

CAPR1
Caprin-1

1

0

High-throughput

0.458

High

352439

PUM1
Pumilio homolog 1

1

0

High-throughput

0.458

High

352441

SMC1A
Structural maintenance of chromosomes protein 1A

1

0

High-throughput

0.458

High

352451

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

352454

LSM12
Protein LSM12

1

0

High-throughput

0.458

High

352458

SMAG2
Protein Smaug homolog 2

1

0

High-throughput

0.458

High

352470

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.458

High

352476

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

352481

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.458

High

352487

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

352490

RP25L
Ribonuclease P protein subunit p25-like protein

1

0

High-throughput

0.458

High

352495

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

352518

ZFR
Zinc finger RNA-binding protein

1

0

High-throughput

0.458

High

352519

CNO6L
CCR4-NOT transcription complex subunit 6-like

1

0

High-throughput

0.458

High

352522

SEBP2
Selenocysteine insertion sequence-binding protein 2

1

0

High-throughput

0.458

High

352527

PKP2
Plakophilin-2

1

0

High-throughput

0.458

High

352532

PYM1
Partner of Y14 and mago

1

0

High-throughput

0.458

High

352535

NTPCR
Cancer-related nucleoside-triphosphatase

1

0

High-throughput

0.458

High

352538

MCRI2
MAPK regulated corepressor interacting protein 2

1

0

High-throughput

0.458

High

352544

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

0

High-throughput

0.458

High

352553

CNO10
CCR4-NOT transcription complex subunit 10

1

0

High-throughput

0.458

High

352561

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

0

High-throughput

0.458

High

352562

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.458

High

352569

MIC19
MICOS complex subunit MIC19

1

0

High-throughput

0.458

High

352571

RTEL1
Regulator of telomere elongation helicase 1

1

0

High-throughput

0.458

High

352574

CNOT2
CCR4-NOT transcription complex subunit 2

1

0

High-throughput

0.458

High

352587

DCTN4
Dynactin subunit 4

1

0

High-throughput

0.458

High

352590

AGO2
Protein argonaute-2

1

0

High-throughput

0.458

High

352591

CNO11
CCR4-NOT transcription complex subunit 11

1

0

High-throughput

0.458

High

352595

AKP8L
A-kinase anchor protein 8-like

1

0

High-throughput

0.458

High

352608

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

352611

NOC2L
Nucleolar complex protein 2 homolog

1

0

High-throughput

0.458

High

352613

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

0

High-throughput

0.458

High

352615

SP16H
FACT complex subunit SPT16

1

0

High-throughput

0.458

High

159306

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

2

High-throughput

0.437

High

174682

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

4

High-throughput

0.437

High

221994

NCK2
Cytoplasmic protein NCK2

1

4

High-throughput

0.437

High

245842

KIF1B
Kinesin-like protein KIF1B

1

1

High-throughput

0.437

High

258704

DNJA2
DnaJ homolog subfamily A member 2

1

1

High-throughput

0.437

High

321140

ERLN2
Erlin-2

1

1

High-throughput

0.437

High

338267

SC24A
Protein transport protein Sec24A

1

3

High-throughput

0.437

High

338391

SC24B
Protein transport protein Sec24B

1

3

High-throughput

0.437

High

352287

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

3

High-throughput

0.437

High

352295

YES
Tyrosine-protein kinase Yes

1

1

High-throughput

0.437

High

352299

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

3

High-throughput

0.437

High

352301

TPM1
Tropomyosin alpha-1 chain

1

1

High-throughput

0.437

High

352303

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.437

High

352305

SPTB1
Spectrin beta chain, erythrocytic

1

4

High-throughput

0.437

High

352319

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

1

High-throughput

0.437

High

352334

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

1

High-throughput

0.437

High

352346

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

1

High-throughput

0.437

High

352349

ACTY
Beta-centractin

1

1

High-throughput

0.437

High

352389

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

3

High-throughput

0.437

High

352390

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

3

High-throughput

0.437

High

352393

TPM4
Tropomyosin alpha-4 chain

1

1

High-throughput

0.437

High

352421

ABR
Active breakpoint cluster region-related protein

1

1

High-throughput

0.437

High

352422

ACACA
Acetyl-CoA carboxylase 1

1

1

Small-scale

0.437

High

352427

CUL2
Cullin-2

1

1

High-throughput

0.437

High

352429

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

5

High-throughput

0.437

High

352448

SC23A
Protein transport protein Sec23A

1

3

High-throughput

0.437

High

352449

SC23B
Protein transport protein Sec23B

1

3

High-throughput

0.437

High

352492

POC1A
POC1 centriolar protein homolog A

1

1

High-throughput

0.437

High

352496

NEDD1
Protein NEDD1

1

2

High-throughput

0.437

High

352501

PDC6I
Programmed cell death 6-interacting protein

1

1

High-throughput

0.437

High

352521

NEB2
Neurabin-2

1

2

High-throughput

0.437

High

352540

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.437

High

352547

UN45A
Protein unc-45 homolog A

1

1

High-throughput

0.437

High

352548

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

352578

SYLC
Leucine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.437

High

352593

NEB1
Neurabin-1

1

2

High-throughput

0.437

High

352337

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

352465

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.407

High

352469

ATL4
ADAMTS-like protein 4

2

0

High-throughput

0.327

High

352477

SPRE2
Sprouty-related, EVH1 domain-containing protein 2

2

0

High-throughput

0.327

High

352503

TRI41
E3 ubiquitin-protein ligase TRIM41

2

0

High-throughput

0.327

High

352530

KR412
Keratin-associated protein 4-12

2

0

High-throughput

0.317

High

352462

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

2

0

High-throughput

0.313

High

352592

PNMA2
Paraneoplastic antigen Ma2

1

0

High-throughput

0.299

High

352588

CHIC2
Cysteine-rich hydrophobic domain-containing protein 2

1

0

High-throughput

0.282

High

292506

RENR
Renin receptor

1

0

High-throughput

0.279

Low

352283

GBA1
Lysosomal acid glucosylceramidase

1

0

High-throughput

0.279

Low

352324

KALM
Anosmin-1

1

0

High-throughput

0.279

Low

352381

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.279

Low

352443

MELT
Ventricular zone-expressed PH domain-containing protein homolog 1

1

0

High-throughput

0.279

Low

352455

GAG2E
G antigen 2E

1

0

High-throughput

0.279

Low

352512

RMD1
Regulator of microtubule dynamics protein 1

1

0

High-throughput

0.279

Low

352533

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.279

Low

352570

PEN2
Gamma-secretase subunit PEN-2

1

0

High-throughput

0.279

Low

352577

KLH14
Kelch-like protein 14

1

0

High-throughput

0.279

Low

352584

TSR3
18S rRNA aminocarboxypropyltransferase

1

0

High-throughput

0.279

Low

129945

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.269

Low

137603

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.269

Low

352282

FETUA
Alpha-2-HS-glycoprotein

1

0

High-throughput

0.269

Low

352310

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.269

Low

352342

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.269

Low

352456

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

0

High-throughput

0.269

Low

352537

EFHD1
EF-hand domain-containing protein D1

1

0

High-throughput

0.269

Low

352580

FBLN5
Fibulin-5

1

0

Small-scale

0.251

Low

71687

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

0

High-throughput

0.249

Low

174884

SC16A
Protein transport protein Sec16A

1

0

High-throughput

0.249

Low

209415

SERA
D-3-phosphoglycerate dehydrogenase

1

0

High-throughput

0.249

Low

228420

LANC1
Glutathione S-transferase LANCL1

1

0

High-throughput

0.249

Low

228779

SCO2
Protein SCO2 homolog, mitochondrial

1

0

High-throughput

0.249

Low

301830

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

0

High-throughput

0.249

Low

352280

MOC2A
Molybdopterin synthase sulfur carrier subunit

1

0

High-throughput

0.249

Low

352281

HBD
Hemoglobin subunit delta

1

0

High-throughput

0.249

Low

352284

APOB
Apolipoprotein B-100

1

0

High-throughput

0.249

Low

352291

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.249

Low

352293

APT
Adenine phosphoribosyltransferase

1

0

High-throughput

0.249

Low

352302

CLCA
Clathrin light chain A

1

0

High-throughput

0.249

Low

352311

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

352317

CBR1
Carbonyl reductase [NADPH] 1

1

0

High-throughput

0.249

Low

352332

NMT1
Glycylpeptide N-tetradecanoyltransferase 1

1

0

High-throughput

0.249

Low

352333

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.249

Low

352350

NAMPT
Nicotinamide phosphoribosyltransferase

1

0

High-throughput

0.249

Low

352403

LAT1
Large neutral amino acids transporter small subunit 1

1

0

High-throughput

0.249

Low

352409

LMNB2
Lamin-B2

1

0

High-throughput

0.249

Low

352428

MOGS
Mannosyl-oligosaccharide glucosidase

1

0

High-throughput

0.249

Low

352446

RCN1
Reticulocalbin-1

1

0

High-throughput

0.249

Low

352453

WASC4
WASH complex subunit 4

1

0

High-throughput

0.249

Low

352459

UBR4
E3 ubiquitin-protein ligase UBR4

1

0

High-throughput

0.249

Low

352461

GKAP1
G kinase-anchoring protein 1

1

0

High-throughput

0.249

Low

352463

MIC13
MICOS complex subunit MIC13

1

0

High-throughput

0.249

Low

352468

LRC31
Leucine-rich repeat-containing protein 31

1

0

High-throughput

0.249

Low

352489

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

352491

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

1

0

High-throughput

0.249

Low

352500

SMAP2
Stromal membrane-associated protein 2

1

0

High-throughput

0.249

Low

352502

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low

352511

EXOC4
Exocyst complex component 4

1

0

High-throughput

0.249

Low

352516

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

352528

NIPS1
Protein NipSnap homolog 1

1

0

High-throughput

0.249

Low

352529

PAIP2
Polyadenylate-binding protein-interacting protein 2

1

0

High-throughput

0.249

Low

352550

HAUS4
HAUS augmin-like complex subunit 4

1

0

High-throughput

0.249

Low

352552

GORS2
Golgi reassembly-stacking protein 2

1

0

High-throughput

0.249

Low

352563

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.249

Low

352565

TXLNG
Gamma-taxilin

1

0

High-throughput

0.249

Low

352566

ATD3A
ATPase family AAA domain-containing protein 3A

1

0

High-throughput

0.249

Low

352575

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

High-throughput

0.249

Low

352579

GBG12

1

0

High-throughput

0.249

Low

352581

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.249

Low

352585

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

0

High-throughput

0.249

Low

352594

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

352599

CC14A
Dual specificity protein phosphatase CDC14A

1

0

High-throughput

0.249

Low

352612

HYOU1
Hypoxia up-regulated protein 1

1

0

High-throughput

0.249

Low

352279

MOC2B
Molybdopterin synthase catalytic subunit

1

0

High-throughput

0.232

Low

352493

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low

352616

PCDGD
Protocadherin gamma-B1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025