HitPredict

Interactor 1: TNFA (P01375)
Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]
Gene: TNF

Interactor 2: NFL (P07196)
Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein)
Gene: NEFL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	20195357
Identification Methods	display technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 233 Hs			1 543
+	Hs
		352440 TNFA_HUMAN (1-233): 1.87e-111: 320: 100.00		K2C8_HUMAN (69-431): 4.2e-132: 394: 36.44
+	Hs
		352467 TNFA_HUMAN (1-233): 1.87e-111: 320: 100.00		K2C5_HUMAN (56-403): 3.13e-64: 221: 31.62
+	Rn
		561404 TNFA_RAT (1-233): 1.51e-91: 270: 78.39		VIME_RAT (69-402): 4.03e-81: 263: 51.50
+	Hs
		213923 TNFA_HUMAN (1-233): 1.87e-111: 320: 100.00		KRT86_HUMAN (238-543): 3.82e-09: 61.1: 13.29