Interactor 1: TNFA (P01375)
Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]
Gene: TNF

Interactor 2: PTPRZ (P23471)
Receptor-type tyrosine-protein phosphatase zeta (R-PTP-zeta) (EC 3.1.3.48) (Protein-tyrosine phosphatase receptor type Z polypeptide 1) (Protein-tyrosine phosphatase receptor type Z polypeptide 2) (R-PTP-zeta-2)
Gene: PTPRZ1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 20195357
Identification Methods display technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TNF~fn3
Common GO terms GO:0005576 - extracellular region
GO:0005886 - plasma membrane
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 233
Hs

1 2315
+ Hs

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Last updated: 15 Jul 2024