HitPredict

Interactor 1: TNFA (P01375)
Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]
Gene: TNF

Interactor 2: DD19B (Q9UMR2)
ATP-dependent RNA helicase DDX19B (EC 3.6.4.13) (DEAD box RNA helicase DEAD5) (DEAD box protein 19B)
Gene: DDX19B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 233 Hs			1 479
+	Hs
		352672 TNFA_HUMAN (1-233): 1.87e-111: 320: 100.00		DDX17_HUMAN (24-474): 5.05e-128: 390: 23.81
+	Hs
		352478 TNFA_HUMAN (1-233): 1.87e-111: 320: 100.00		DDX5_HUMAN (24-475): 1.07e-128: 388: 23.54
+	Hs
		133817 TNFA_HUMAN (1-233): 1.87e-111: 320: 100.00		DDX3X_HUMAN (23-476): 7.98e-122: 372: 25.26
+	Hs
		352427 TNFB_HUMAN (58-233): 1.45e-43: 147: 30.06		DD19B_HUMAN (1-479): 2.69e-141: 416: 100.00