HitPredict

Interactor 1: IFNB (P01574)
Interferon beta (IFN-beta) (Fibroblast interferon)
Gene: IFNB1

Interactor 2: IRF8 (Q02556)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (H-ICSBP) (ICSBP)
Gene: IRF8

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	9092512
Identification Methods	electrophoretic mobility supershift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 187 Hs			1 426
+	Mm
		352888 IFNB_MOUSE (1-187): 4.49e-60: 186: 49.20		IRF8_MOUSE (1-426): 0: 579: 89.67
+	Hs
		352882 IFNB_HUMAN (1-187): 1.53e-76: 228: 100.00		IRF5_HUMAN (9-414): 5.23e-156: 451: 30.36
+	Hs
		352753 IFNA1_HUMAN (10-186): 1.82e-74: 223: 31.49		IRF5_HUMAN (9-414): 5.23e-156: 451: 30.36
+	Hs
		352842 IFN14_HUMAN (10-186): 1.71e-71: 216: 32.60		IRF5_HUMAN (9-414): 5.23e-156: 451: 30.36
+	Mm
		352891 IFNB_MOUSE (1-187): 4.49e-60: 186: 49.20		IRF5_MOUSE (9-424): 7.58e-159: 459: 31.00
+	Hs
		352883 IFNB_HUMAN (1-187): 1.53e-76: 228: 100.00		IRF3_HUMAN (9-399): 1.44e-139: 407: 26.68
+	Hs
		352755 IFNA1_HUMAN (10-186): 1.82e-74: 223: 31.49		IRF3_HUMAN (9-399): 1.44e-139: 407: 26.68
+	Hs
		352770 IFNA2_HUMAN (23-187): 2.08e-72: 218: 33.73		IRF3_HUMAN (9-399): 1.44e-139: 407: 26.68
+	Hs
		352788 IFNA7_HUMAN (9-186): 3.79e-72: 218: 32.62		IRF3_HUMAN (9-399): 1.44e-139: 407: 26.68
+	Hs
		352844 IFN14_HUMAN (10-186): 1.71e-71: 216: 32.60		IRF3_HUMAN (9-399): 1.44e-139: 407: 26.68
+	Hs
		352885 IFNB_HUMAN (1-187): 1.53e-76: 228: 100.00		IRF7_HUMAN (12-385): 3.06e-114: 345: 21.91
+	Hs
		352758 IFNA1_HUMAN (10-186): 1.82e-74: 223: 31.49		IRF7_HUMAN (12-385): 3.06e-114: 345: 21.91
+	Hs
		352775 IFNA2_HUMAN (23-187): 2.08e-72: 218: 33.73		IRF7_HUMAN (12-385): 3.06e-114: 345: 21.91
+	Hs
		352791 IFNA7_HUMAN (9-186): 3.79e-72: 218: 32.62		IRF7_HUMAN (12-385): 3.06e-114: 345: 21.91
+	Hs
		352848 IFN14_HUMAN (10-186): 1.71e-71: 216: 32.60		IRF7_HUMAN (12-385): 3.06e-114: 345: 21.91
+	Hs
		352861 IFNB_HUMAN (1-187): 1.53e-76: 228: 100.00		IRF1_HUMAN (9-187): 2.59e-62: 206: 33.69
+	Hs
		352745 IFNA1_HUMAN (10-186): 1.82e-74: 223: 31.49		IRF1_HUMAN (9-187): 2.59e-62: 206: 33.69
+	Hs
		352766 IFNA2_HUMAN (23-187): 2.08e-72: 218: 33.73		IRF1_HUMAN (9-187): 2.59e-62: 206: 33.69
+	Hs
		352837 IFN14_HUMAN (10-186): 1.71e-71: 216: 32.60		IRF1_HUMAN (9-187): 2.59e-62: 206: 33.69
+	Hs
		352862 IFNB_HUMAN (1-187): 1.53e-76: 228: 100.00		IRF2_HUMAN (9-167): 4.69e-53: 182: 36.88