Interactor 1: IL1A (P01582)
Interleukin-1 alpha (IL-1 alpha)
Gene: IL1A

Interactor 2: IL1R1 (P13504)
Interleukin-1 receptor type 1 (IL-1R-1) (IL-1RT-1) (IL-1RT1) (EC 3.2.2.6) (CD121 antigen-like family member A) (Interleukin-1 receptor alpha) (IL-1R-alpha) (Interleukin-1 receptor type I) (p80) (CD antigen CD121a) [Cleaved into: Interleukin-1 receptor type 1, membrane form (mIL-1R1) (mIL-1RI); Interleukin-1 receptor type 1, soluble form (sIL-1R1) (sIL-1RI)]
Gene: IL1R1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17507369
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IL1~I-set, IL1~Ig_2
Common GO terms GO:0005615 - extracellular space
GO:0006954 - inflammatory response
GO:0009986 - cell surface
GO:0019221 - cytokine-mediated signaling pathway
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 270
Mm

1 576
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024