Interactor 1: IL1B (P01584)
Interleukin-1 beta (IL-1 beta) (Catabolin)
Gene: IL1B

Interactor 2: IL1R2 (P27930)
Interleukin-1 receptor type 2 (IL-1R-2) (IL-1RT-2) (IL-1RT2) (CD121 antigen-like family member B) (CDw121b) (IL-1 type II receptor) (Interleukin-1 receptor beta) (IL-1R-beta) (Interleukin-1 receptor type II) (CD antigen CD121b) [Cleaved into: Interleukin-1 receptor type 2, membrane form (mIL-1R2) (mIL-1RII); Interleukin-1 receptor type 2, soluble form (sIL-1R2) (sIL-1RII)]
Gene: IL1R2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 1833184, 7878046, 20802483
Identification Methods competition binding, protein cross-linking with a bifunctional reagent, x-ray crystallography
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IL1~ig
Common GO terms GO:0005576 - extracellular region
GO:0006955 - immune response
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 269
Hs

1 398
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Last updated: 15 Jul 2024