Interactor 1: IL1B (P01584)
Interleukin-1 beta (IL-1 beta) (Catabolin)
Gene: IL1B

Interactor 2: IRF8 (Q02556)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (H-ICSBP) (ICSBP)
Gene: IRF8

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 18566416, 17386941
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0006955 - immune response
GO:0032729 - positive regulation of type II interferon production
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0071222 - cellular response to lipopolysaccharide
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 269
Hs

1 426
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024