Interactor 1: IL1B (P01584)
Interleukin-1 beta (IL-1 beta) (Catabolin)
Gene: IL1B

Interactor 2: IL1AP (Q9NPH3)
Interleukin-1 receptor accessory protein (IL-1 receptor accessory protein) (IL-1RAcP) (EC 3.2.2.6) (Interleukin-1 receptor 3) (IL-1R-3) (IL-1R3)
Gene: IL1RAP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.767

The method score is based on:

Property Details
Experiments 16306937, 20802483
Identification Methods anti bait coimmunoprecipitation, surface plasmon resonance
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains IL1~Ig_6
Common GO terms GO:0005149 - interleukin-1 receptor binding
GO:0005576 - extracellular region
GO:0006954 - inflammatory response
GO:0006955 - immune response
GO:0032755 - positive regulation of interleukin-6 production
and 1 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 269
Hs

1 570
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Last updated: 15 Jul 2024