Interactor 1: CD8A (P01732)
T-cell surface glycoprotein CD8 alpha chain (T-lymphocyte differentiation antigen T8/Leu-2) (CD antigen CD8a)
Gene: CD8A

Interactor 2: CD3D (P04234)
T-cell surface glycoprotein CD3 delta chain (T-cell receptor T3 delta chain) (CD antigen CD3d)
Gene: CD3D

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.90 0.687

The method score is based on:

Property Details
Experiments 12215456
Identification Methods fluorescent resonance energy transfer, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ig_4~V-set
Common GO terms GO:0002250 - adaptive immune response
GO:0005886 - plasma membrane
GO:0007166 - cell surface receptor signaling pathway
GO:0009897 - external side of plasma membrane
GO:0042101 - T cell receptor complex
and 1 others

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Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024