Interactor 1: CD8A (P01732)
T-cell surface glycoprotein CD8 alpha chain (T-lymphocyte differentiation antigen T8/Leu-2) (CD antigen CD8a)
Gene: CD8A

Interactor 2: HLAC (P10321)
HLA class I histocompatibility antigen, C alpha chain (HLA-C) (HLA-Cw) (Human leukocyte antigen C)
Gene: HLA-C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 10809759, 12853576
Identification Methods pull down, surface plasmon resonance
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~V-set, MHC_I~V-set
Common GO terms GO:0002250 - adaptive immune response
GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0009897 - external side of plasma membrane
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 235
Hs

1 366
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024