HitPredict

Interactor 1: IGHG1 (P01857)
Immunoglobulin heavy constant gamma 1 (Ig gamma-1 chain C region) (Ig gamma-1 chain C region EU) (Ig gamma-1 chain C region KOL) (Ig gamma-1 chain C region NIE)
Gene: IGHG1

Interactor 2: Q8N355 (Q8N355)
IGL@ protein
Gene: IGL@

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	15174051
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	C1-set~C1-set, C1-set~V-set
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 399 Hs			1 234
+	Hs
		353631 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		IGLL1_HUMAN (110-234): 2.04e-41: 142: 78.40
+	Hs
		353621 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		IGLC1_HUMAN (129-234): 8.08e-38: 129: 96.23
+	Mm
		353201 GCAM_MOUSE (2-399): 2.18e-94: 290: 66.92		KV3A8_MOUSE (20-128): 1.44e-45: 149: 50.00
+	Hs
		353203 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		LV147_HUMAN (1-112): 3.75e-28: 105: 56.14
+	Hs
		353208 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		LV208_HUMAN (1-114): 3.92e-26: 99.8: 54.70
+	Hs
		353596 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		IGHG2_HUMAN (130-231): 2.23e-22: 96: 31.73
+	Hs
		353748 IGHG3_HUMAN (1-399): 7.71e-97: 298: 83.86		IGHG2_HUMAN (130-231): 2.23e-22: 96: 31.73
+	Hs
		353707 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		TITIN_HUMAN (22-215): 9.96e-10: 60.3: 15.98
+	Hs
		353595 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		IGHG1_HUMAN (134-232): 2.93e-09: 58.2: 23.81
+	Mm
		353195 IGG2B_MOUSE (2-399): 1.27e-94: 291: 63.95		KV2A7_MOUSE (22-127): 2.63e-19: 82: 46.02
+	Mm
		353194 GCAM_MOUSE (2-399): 2.18e-94: 290: 66.92		KV2A7_MOUSE (22-127): 2.63e-19: 82: 46.02
+	Mm
		353202 IGHG1_MOUSE (1-329): 1.44e-67: 218: 60.79		KV3AD_MOUSE (20-128): 2.46e-45: 148: 47.37
+	Mm
		353580 IGHG1_MOUSE (1-329): 1.44e-67: 218: 60.79		LAC1_MOUSE (130-234): 6.92e-44: 144: 71.43
+	Hs
		353598 IGHG4_HUMAN (1-399): 5.43e-99: 301: 91.98		IGHG1_HUMAN (134-232): 2.93e-09: 58.2: 23.81
+	Hs
		353597 IGHG3_HUMAN (1-399): 7.71e-97: 298: 83.86		IGHG1_HUMAN (134-232): 2.93e-09: 58.2: 23.81
+	Hs
		353181 IGHA1_HUMAN (1-374): 5.12e-63: 209: 29.85		KVD40_HUMAN (1-113): 2.62e-37: 128: 43.80
+	Mm
		353221 IGHG1_MOUSE (1-329): 1.44e-67: 218: 60.79		LV1B_MOUSE (1-129): 3.91e-20: 84.3: 43.18
+	Mm
		353196 IGHG1_MOUSE (1-329): 1.44e-67: 218: 60.79		KV2A7_MOUSE (22-127): 2.63e-19: 82: 46.02
+	Mm
		353224 IGHG1_MOUSE (1-329): 1.44e-67: 218: 60.79		LV1E_MOUSE (1-129): 4.54e-19: 81.6: 41.67