Protein: THIOM
Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2)

Gene: THIOM, TXN2
Organism: Homo sapiens
Interactions: 110
UniProt ID: Q99757

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0005730 - nucleolus
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006979 - response to oxidative stress

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1306343

TXNIP
Thioredoxin-interacting protein

2

5

High-throughput

0.811

High

1216441

RBM45
RNA-binding protein 45

3

1

High-throughput

0.779

High

49183

CIB4
Calcium and integrin-binding family member 4

2

1

High-throughput

0.700

High

624364

MYL9
Myosin regulatory light polypeptide 9

2

3

High-throughput

0.700

High

1164256

ATRAP
Type-1 angiotensin II receptor-associated protein

3

0

High-throughput

0.646

High

1224271

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

4

1

High-throughput

0.637

High

978871

TF65
Transcription factor p65

3

3

Small-scale

0.636

High

585045

RO52
E3 ubiquitin-protein ligase TRIM21

3

1

High-throughput

0.616

High

825337

RPIA
Ribose-5-phosphate isomerase

3

1

High-throughput

0.616

High

925985

AP2B1
AP-2 complex subunit beta

3

1

High-throughput

0.616

High

1075076

MARE2
Microtubule-associated protein RP/EB family member 2

3

3

High-throughput

0.616

High

1127138

MTUS2
Microtubule-associated tumor suppressor candidate 2

3

2

High-throughput

0.616

High

1286632

COAC
Phosphopantothenoylcysteine decarboxylase

3

1

High-throughput

0.616

High

1293851

MR1L1
MORF4 family-associated protein 1-like 1

3

2

High-throughput

0.616

High

1306359

MARE3
Microtubule-associated protein RP/EB family member 3

3

3

High-throughput

0.616

High

316528

ETHE1
Persulfide dioxygenase ETHE1, mitochondrial

2

1

High-throughput

0.606

High

1306352

TFP11
Tuftelin-interacting protein 11

2

1

High-throughput

0.606

High

1287726

GASP2
G-protein coupled receptor-associated sorting protein 2

3

2

High-throughput

0.597

High

423342

PDIA1
Protein disulfide-isomerase

1

18

High-throughput

0.590

High

278520

SPF27
Pre-mRNA-splicing factor SPF27

2

0

High-throughput

0.580

High

727183

DDIT3
DNA damage-inducible transcript 3 protein

2

0

High-throughput

0.580

High

1306337

UQCC2
Ubiquinol-cytochrome c reductase complex assembly factor 2

2

0

High-throughput

0.580

High

215923

ZBT14
Zinc finger and BTB domain-containing protein 14

1

2

High-throughput

0.573

High

1306357

RABX5
Rab5 GDP/GTP exchange factor

1

4

High-throughput

0.573

High

1306358

CHIP
E3 ubiquitin-protein ligase CHIP

1

5

High-throughput

0.573

High

377636

GCR
Glucocorticoid receptor

1

12

Small-scale

0.561

High

1299932

FMNL2
Formin-like protein 2

2

1

High-throughput

0.560

High

62404

GG6L9
Golgin subfamily A member 6-like protein 9

2

4

High-throughput

0.553

High

180427

MAGB2
Melanoma-associated antigen B2

2

2

High-throughput

0.553

High

360658

SPTA1
Spectrin alpha chain, erythrocytic 1

2

5

High-throughput

0.553

High

795833

MAGA4
Melanoma-associated antigen 4

2

2

High-throughput

0.553

High

945720

NGAL
Neutrophil gelatinase-associated lipocalin

2

2

High-throughput

0.553

High

1136605

FHL5
Four and a half LIM domains protein 5

2

2

High-throughput

0.553

High

1146488

KAZRN
Kazrin

2

1

High-throughput

0.553

High

1161656

GASP3
G protein-coupled receptor associated sorting protein 3

2

2

High-throughput

0.553

High

1189637

K1C27
Keratin, type I cytoskeletal 27

2

4

High-throughput

0.553

High

1231749

AN36B
Ankyrin repeat domain-containing protein 36B

2

6

High-throughput

0.553

High

1234043

EFC4A
EF-hand calcium-binding domain-containing protein 4A

2

2

High-throughput

0.553

High

1302725

PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B

2

6

High-throughput

0.553

High

1306339

GTPB2
GTP-binding protein 2

2

3

High-throughput

0.553

High

1306346

CHM1A
Charged multivesicular body protein 1a

2

4

High-throughput

0.553

High

1306351

ABI3
ABI gene family member 3

2

3

High-throughput

0.553

High

1306361

MOFA1
MORF4 family-associated protein 1

2

2

High-throughput

0.553

High

796337

MAGAB
Melanoma-associated antigen 11

1

2

High-throughput

0.523

High

899010

PSME3
Proteasome activator complex subunit 3

1

1

High-throughput

0.523

High

1076517

TRIP6
Thyroid receptor-interacting protein 6

1

3

High-throughput

0.523

High

1149310

K1C40
Keratin, type I cytoskeletal 40

1

6

High-throughput

0.523

High

1297605

ODAD1
Outer dynein arm-docking complex subunit 1

1

8

High-throughput

0.523

High

898449

RS3A
Small ribosomal subunit protein eS1

1

2

High-throughput

0.515

High

1306360

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

9

Small-scale

0.501

High

1306356

PRAF1
Prenylated Rab acceptor protein 1

1

1

High-throughput

0.494

High

791907

HD
Huntingtin

1

0

High-throughput

0.493

High

214650

MYO1B
Unconventional myosin-Ib

1

4

High-throughput

0.489

High

813705

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.489

High

1306347

ANLN
Anillin

1

2

High-throughput

0.489

High

408909

K1C18
Keratin, type I cytoskeletal 18

1

2

High-throughput

0.481

High

1151201

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

1169156

Q6ZN96
cDNA FLJ16308 fis, clone PUAEN2006335

1

1

High-throughput

0.470

High

776381

MLH1
DNA mismatch repair protein Mlh1

1

1

Small-scale

0.464

High

1306342

SHRPN
Sharpin

1

0

High-throughput

0.460

High

378142

PRIO
Major prion protein

1

1

High-throughput

0.445

High

393825

ALDOB
Fructose-bisphosphate aldolase B

1

7

High-throughput

0.439

High

443751

VIME
Vimentin

1

5

High-throughput

0.439

High

838226

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

1306349

ZSC32
Zinc finger and SCAN domain-containing protein 32

1

5

High-throughput

0.439

High

1120164

Q53ET4
Serine hydroxymethyltransferase

1

0

High-throughput

0.438

High

101110

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

304308

UBR5
E3 ubiquitin-protein ligase UBR5

1

10

Small-scale

0.437

High

489226

H14
Histone H1.4

1

3

High-throughput

0.437

High

559909

H12
Histone H1.2

1

3

High-throughput

0.437

High

1305584

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

7

Small-scale

0.437

High

1306355

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.437

High

341397

PLMN
Plasminogen

1

2

High-throughput

0.417

High

361909

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

3

High-throughput

0.417

High

362025

FIBG
Fibrinogen gamma chain

1

3

High-throughput

0.417

High

670175

MARCS
Myristoylated alanine-rich C-kinase substrate

1

3

High-throughput

0.417

High

929981

ACTG
Actin, cytoplasmic 2

1

6

High-throughput

0.417

High

1189789

MYH14
Myosin-14

1

1

High-throughput

0.417

High

214733

SSNA1
Microtubule nucleation factor SSNA1

3

0

High-throughput

0.352

High

1230706

VPS52
Vacuolar protein sorting-associated protein 52 homolog

3

0

High-throughput

0.352

High

1293755

REEP6
Receptor expression-enhancing protein 6

3

0

High-throughput

0.352

High

351612

COLI
Pro-opiomelanocortin

2

0

High-throughput

0.316

High

600051

SAT1
Diamine acetyltransferase 1

2

0

High-throughput

0.316

High

777252

PEX19
Peroxisomal biogenesis factor 19

2

0

High-throughput

0.316

High

1126561

TTC32
Tetratricopeptide repeat protein 32

2

0

High-throughput

0.316

High

1229559

SYCE1
Synaptonemal complex central element protein 1

2

0

High-throughput

0.316

High

1245758

CEP70
Centrosomal protein of 70 kDa

2

0

High-throughput

0.316

High

1254162

MIPO1
Mirror-image polydactyly gene 1 protein

2

0

High-throughput

0.316

High

1287093

HAUS1
HAUS augmin-like complex subunit 1

2

0

High-throughput

0.316

High

1298874

GUCD1
Protein GUCD1

2

0

High-throughput

0.316

High

1306219

MDFI
MyoD family inhibitor

2

0

High-throughput

0.316

High

1306338

HAUS8
HAUS augmin-like complex subunit 8

2

0

High-throughput

0.316

High

1306340

CDCA4
Cell division cycle-associated protein 4

2

0

High-throughput

0.316

High

1306341

ZMY12
Zinc finger MYND domain-containing protein 12

2

0

High-throughput

0.316

High

1306344

STN1
CST complex subunit STN1

2

0

High-throughput

0.316

High

1306345

CSTP1
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1

2

0

High-throughput

0.316

High

1306350

TMOD4
Tropomodulin-4

2

0

High-throughput

0.316

High

1306354

CGBP1
CGG triplet repeat-binding protein 1

2

0

High-throughput

0.316

High

687166

DCTD
Deoxycytidylate deaminase

1

0

High-throughput

0.299

High

1224877

FAM9B
Protein FAM9B

1

0

High-throughput

0.299

High

1286781

TIFA
TRAF-interacting protein with FHA domain-containing protein A

1

0

High-throughput

0.299

High

1235181

CB073
Uncharacterized protein C2orf73

1

0

High-throughput

0.279

Low

1297385

CB050
Uncharacterized protein C2orf50

1

0

High-throughput

0.279

Low

328458

RECK
Reversion-inducing cysteine-rich protein with Kazal motifs

1

0

High-throughput

0.269

Low

1306353

I36RA
Interleukin-36 receptor antagonist protein

1

0

High-throughput

0.269

Low

1241935

CC197
Uncharacterized protein CCDC197

1

0

High-throughput

0.268

Low

1205187

NUTM1
NUT family member 1

1

0

High-throughput

0.251

Low

1306348

THAP1
THAP domain-containing protein 1

1

0

High-throughput

0.251

Low

373059

VTNC
Vitronectin

1

0

High-throughput

0.238

Low

1053806

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024