HitPredict

Interactor 1: IGHG1 (P01857)
Immunoglobulin heavy constant gamma 1 (Ig gamma-1 chain C region) (Ig gamma-1 chain C region EU) (Ig gamma-1 chain C region KOL) (Ig gamma-1 chain C region NIE)
Gene: IGHG1

Interactor 2: NEMO (Q9Y6K9)
NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 399 Hs			1 419
+	Hs
		353868 IGHG3_HUMAN (1-399): 7.71e-97: 298: 83.86		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		1198815 Q86TT2_HUMAN (25-329): 1.75e-58: 196: 79.83		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		1263176 PALLD_HUMAN (43-358): 1.5e-10: 65.4: 11.39		OPTN_HUMAN (67-418): 2.78e-38: 147: 27.25
+	Hs
		1264783 TITIN_HUMAN (7-349): 6.13e-09: 60.4: 9.88		OPTN_HUMAN (67-418): 2.78e-38: 147: 27.25
+	Hs
		1077872 MYLK_HUMAN (159-325): 2.13e-09: 61.6: 11.31		MYO5A_HUMAN (38-342): 1.7e-24: 108: 14.65
+	Hs
		551790 TITIN_HUMAN (7-349): 6.13e-09: 60.4: 9.88		DESP_HUMAN (45-363): 7.32e-21: 97.8: 15.84
+	Hs
		724937 PALLD_HUMAN (43-358): 1.5e-10: 65.4: 11.39		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		724846 MYLK_HUMAN (159-325): 2.13e-09: 61.6: 11.31		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93