HitPredict

Interactor 1: IGHG3 (P01860)
Immunoglobulin heavy constant gamma 3 (HDC) (Heavy chain disease protein) (Ig gamma-3 chain C region)
Gene: IGHG3

Interactor 2: RN115 (Q9Y4L5)
E3 ubiquitin-protein ligase RNF115 (EC 2.3.2.27) (RING finger protein 115) (RING-type E3 ubiquitin transferase RNF115) (Rab7-interacting RING finger protein) (Rabring 7) (Zinc finger protein 364)
Gene: RNF115

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 446 Hs			1 304
+	Hs
		353746 IGHG1_HUMAN (1-446): 6.57e-137: 400: 84.53		RN115_HUMAN (1-304): 2.11e-80: 247: 100.00
+	Hs
		353835 IGHG2_HUMAN (1-446): 1.51e-131: 386: 78.25		RN115_HUMAN (1-304): 2.11e-80: 247: 100.00
+	Hs
		353901 IGHG4_HUMAN (1-446): 1.07e-128: 379: 82.29		RN115_HUMAN (1-304): 2.11e-80: 247: 100.00
+	Hs
		48919 IGLC7_HUMAN (271-372): 1.09e-29: 113: 32.69		RN115_HUMAN (1-304): 2.11e-80: 247: 100.00
+	Hs
		382615 DPB1_HUMAN (156-406): 3.46e-59: 196: 17.46		RN149_HUMAN (54-297): 8.58e-40: 145: 17.05
+	Hs
		354966 DRB1_HUMAN (140-383): 2.96e-58: 194: 16.53		RN149_HUMAN (54-297): 8.58e-40: 145: 17.05