HitPredict

Interactor 1: IGHM (P01871)
Immunoglobulin heavy constant mu (Ig mu chain C region) (Ig mu chain C region BOT) (Ig mu chain C region GAL) (Ig mu chain C region OU)
Gene: IGHM

Interactor 2: CERS3 (Q8IU89)
Ceramide synthase 3 (CerS3) (Dihydroceramide synthase 3) (LAG1 longevity assurance homolog 3) (Sphingosine N-acyltransferase CERS3) (EC 2.3.1.24) (Ultra-long-chain ceramide synthase CERS3) (EC 2.3.1.298) (Very-long-chain ceramide synthase CERS3) (EC 2.3.1.297)
Gene: CERS3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 474 Hs			1 383
+	Hs
		353885 IGHG4_HUMAN (1-315): 9.2e-34: 133: 23.10		CERS3_HUMAN (1-383): 1.64e-136: 396: 100.00
+	Hs
		530185 NCAM1_HUMAN (2-454): 1.33e-21: 100: 9.55		CERS2_HUMAN (1-341): 1.18e-140: 406: 54.68
+	Hs
		353694 IGHG1_HUMAN (5-220): 4.48e-16: 82: 15.98		CERS3_HUMAN (1-383): 1.64e-136: 396: 100.00
+	Hs
		353791 IGHG2_HUMAN (7-220): 4.43e-15: 78.9: 15.21		CERS3_HUMAN (1-383): 1.64e-136: 396: 100.00
+	Hs
		353853 IGHG3_HUMAN (106-233): 5.08e-11: 66.6: 17.97		CERS3_HUMAN (1-383): 1.64e-136: 396: 100.00
+	Hs
		48914 IGLC7_HUMAN (107-212): 2.2e-12: 65.2: 25.47		CERS3_HUMAN (1-383): 1.64e-136: 396: 100.00