HitPredict

Interactor 1: IGHA1 (P01876)
Immunoglobulin heavy constant alpha 1 (Ig alpha-1 chain C region) (Ig alpha-1 chain C region BUR) (Ig alpha-1 chain C region TRO)
Gene: IGHA1

Interactor 2: STK4 (Q13043)
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]
Gene: STK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	23386615
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 398 Hs			1 487
+	Hs
		353771 IGHG2_HUMAN (1-392): 4.13e-72: 232: 29.40		STK4_HUMAN (1-487): 7.89e-170: 489: 100.00
+	Hs
		353772 IGHG2_HUMAN (1-392): 4.13e-72: 232: 29.40		STK3_HUMAN (1-487): 2.36e-147: 432: 72.47
+	Hs
		353931 IGHM_HUMAN (2-370): 4.97e-21: 96.6: 18.49		STK4_HUMAN (1-487): 7.89e-170: 489: 100.00
+	Hs
		353932 IGHM_HUMAN (2-370): 4.97e-21: 96.6: 18.49		STK3_HUMAN (1-487): 2.36e-147: 432: 72.47
+	Hs
		1026915 MYLK_HUMAN (3-354): 2.79e-21: 98.6: 9.90		PAK2_HUMAN (8-300): 1.44e-118: 359: 40.26
+	Hs
		1026170 MYLK_HUMAN (3-354): 2.79e-21: 98.6: 9.90		PAK1_HUMAN (3-305): 1.66e-117: 357: 40.91
+	Hs
		530144 NCAM1_HUMAN (12-374): 1e-18: 90.5: 13.93		KAPCA_HUMAN (14-319): 7.68e-123: 364: 26.90
+	Dm
		219809 O44924_DROME (5-138): 1.15e-10: 65.4: 13.97		PAK_DROME (3-301): 3.9e-117: 361: 39.81