HitPredict

Interactor 1: B2MG (P01887)
Beta-2-microglobulin
Gene: B2m

Interactor 2: HA17 (P14429)
H-2 class I histocompatibility antigen, Q7 alpha chain (QA-2 antigen)
Gene: H2-Q7

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	11738047
Identification Methods	x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~C1-set, C1-set~MHC_I
Common GO terms	GO:0001916 - positive regulation of T cell mediated cytotoxicity GO:0005615 - extracellular space GO:0009897 - external side of plasma membrane GO:0030670 - phagocytic vesicle membrane GO:0042605 - peptide antigen binding and 1 others more... GO:0042612 - MHC class I protein complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 119 Mm			1 334
+	Hs
		382258 HLAA_HUMAN (2-116): 6.78e-44: 148: 20.34		HLAA_HUMAN (1-334): 2.14e-155: 441: 66.47
+	Hs
		382467 HLAA_HUMAN (2-116): 6.78e-44: 148: 20.34		Q860B5_HUMAN (23-334): 1.24e-148: 422: 70.51
+	Hs
		382299 HLAA_HUMAN (2-116): 6.78e-44: 148: 20.34		HLAG_HUMAN (1-334): 8.86e-147: 418: 64.97
+	Hs
		488119 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		HLAG_HUMAN (1-334): 8.86e-147: 418: 64.97
+	Hs
		354248 HLAA_HUMAN (2-116): 6.78e-44: 148: 20.34		HLAB_HUMAN (1-314): 2.12e-145: 416: 68.15
+	Hs
		354258 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		HLAB_HUMAN (1-314): 2.12e-145: 416: 68.15
+	Hs
		354240 HLAH_HUMAN (7-117): 1.23e-42: 144: 21.93		HLAB_HUMAN (1-314): 2.12e-145: 416: 68.15
+	Hs
		354627 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		HLAH_HUMAN (1-334): 7.83e-143: 409: 64.97
+	Hs
		382277 HLAA_HUMAN (2-116): 6.78e-44: 148: 20.34		HLAC_HUMAN (1-310): 1.49e-140: 404: 68.71
+	Hs
		488101 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		HLAC_HUMAN (1-310): 1.49e-140: 404: 68.71
+	Hs
		382286 HLAA_HUMAN (2-116): 6.78e-44: 148: 20.34		HLAE_HUMAN (17-332): 9.69e-138: 396: 65.51
+	Hs
		488112 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		HLAE_HUMAN (17-332): 9.69e-138: 396: 65.51
+	Hs
		354630 HLAH_HUMAN (7-117): 1.23e-42: 144: 21.93		HLAE_HUMAN (17-332): 9.69e-138: 396: 65.51
+	Hs
		382321 HLAA_HUMAN (2-116): 6.78e-44: 148: 20.34		HLAF_HUMAN (1-334): 6.76e-134: 386: 63.47
+	Hs
		488136 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		HLAF_HUMAN (1-334): 6.76e-134: 386: 63.47
+	Hs
		488259 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		Q6F3D7_HUMAN (23-295): 4.74e-134: 384: 73.63
+	Hs
		488329 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		HMR1_HUMAN (2-334): 2.92e-108: 321: 37.61
+	Hs
		488390 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		Q9MY50_HUMAN (1-203): 1.27e-96: 286: 67.49