Protein: TTC28
Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio)

Gene: TTC28
Organism: Homo sapiens
Interactions: 106
UniProt ID: Q96AY4

Gene Ontology (top 5):
GO:0000922 - spindle pole
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0007346 - regulation of mitotic cell cycle
GO:0019900 - kinase binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1383787

RBX2
RING-box protein 2

1

2

High-throughput

0.691

High

222171

NCK2
Cytoplasmic protein NCK2

3

7

High-throughput

0.667

High

938123

ANM2
Protein arginine N-methyltransferase 2

3

6

High-throughput

0.667

High

1383777

CAB45
45 kDa calcium-binding protein

3

5

High-throughput

0.667

High

966717

1433G
14-3-3 protein gamma

3

20

High-throughput

0.650

High

1049647

1433F
14-3-3 protein eta

3

20

High-throughput

0.650

High

1383783

DOCK5
Dedicator of cytokinesis protein 5

2

1

High-throughput

0.628

High

730127

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.611

High

971857

1433E
14-3-3 protein epsilon

2

7

High-throughput

0.611

High

774544

BASI
Basigin

3

5

High-throughput

0.609

High

318038

TOM70
Mitochondrial import receptor subunit TOM70

1

17

High-throughput

0.595

High

1326294

NIN
Ninein

2

9

High-throughput

0.584

High

1383799

NINL
Ninein-like protein

2

11

High-throughput

0.584

High

191379

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

2

3

High-throughput

0.574

High

549848

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

1

High-throughput

0.574

High

1330823

TSYL6
Testis-specific Y-encoded-like protein 6

2

6

High-throughput

0.574

High

1383800

PCDGD
Protocadherin gamma-B1

2

2

High-throughput

0.574

High

943606

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

3

High-throughput

0.541

High

407680

S100B
Protein S100-B

1

3

High-throughput

0.536

High

594075

NCK1
SH2/SH3 adapter protein NCK1

1

7

High-throughput

0.536

High

909127

NEK4
Serine/threonine-protein kinase Nek4

1

9

High-throughput

0.536

High

1383785

PAK6
Serine/threonine-protein kinase PAK 6

1

7

High-throughput

0.536

High

1383802

SNCAP
Synphilin-1

1

7

High-throughput

0.536

High

260786

RAMP2
Receptor activity-modifying protein 2

1

0

High-throughput

0.513

High

303690

JTB
Protein JTB

1

0

High-throughput

0.513

High

407200

CD3D
T-cell surface glycoprotein CD3 delta chain

1

0

High-throughput

0.513

High

1197167

KHDC1
KH homology domain-containing protein 1

1

0

High-throughput

0.513

High

1349253

MYBPP
MYCBP-associated protein

1

0

High-throughput

0.513

High

1383786

BABA2
BRISC and BRCA1-A complex member 2

1

0

High-throughput

0.513

High

374834

RASH
GTPase HRas

1

4

Small-scale

0.501

High

508398

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

8

High-throughput

0.501

High

380330

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

2

High-throughput

0.489

High

427923

ICAM1
Intercellular adhesion molecule 1

1

2

High-throughput

0.489

High

567051

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

3

High-throughput

0.489

High

599125

CBPE
Carboxypeptidase E

1

1

High-throughput

0.489

High

848540

MAGA8
Melanoma-associated antigen 8

1

3

High-throughput

0.489

High

1249726

AEGP
Apical endosomal glycoprotein

1

3

High-throughput

0.489

High

1383798

NCKP1
Nck-associated protein 1

1

1

High-throughput

0.489

High

1383801

NPTN
Neuroplastin

1

5

High-throughput

0.489

High

61572

VWA8
von Willebrand factor A domain-containing protein 8

1

2

High-throughput

0.479

High

324191

CE152
Centrosomal protein of 152 kDa

1

6

High-throughput

0.479

High

404307

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

412407

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.479

High

552665

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

2

High-throughput

0.479

High

691315

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

799377

BRCA1
Breast cancer type 1 susceptibility protein

1

8

High-throughput

0.479

High

891274

GSK3A
Glycogen synthase kinase-3 alpha

1

11

High-throughput

0.479

High

891723

GSK3B
Glycogen synthase kinase-3 beta

1

12

High-throughput

0.479

High

990583

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

1108011

SQSTM
Sequestosome-1

1

3

High-throughput

0.479

High

1109971

HDAC1
Histone deacetylase 1

1

5

High-throughput

0.479

High

1248170

SAS6
Spindle assembly abnormal protein 6 homolog

1

8

High-throughput

0.479

High

1254968

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1331536

CE120
Centrosomal protein of 120 kDa

1

7

High-throughput

0.479

High

1363814

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

1

High-throughput

0.479

High

1383774

BICD1
Protein bicaudal D homolog 1

1

7

High-throughput

0.479

High

1383776

LZTS2
Leucine zipper putative tumor suppressor 2

1

11

High-throughput

0.479

High

1383780

WWTR1
WW domain-containing transcription regulator protein 1

1

13

High-throughput

0.479

High

1383781

ATG5
Autophagy protein 5

1

2

High-throughput

0.479

High

1383782

PKHA4
Pleckstrin homology domain-containing family A member 4

1

19

High-throughput

0.479

High

1383790

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1383796

MARE3
Microtubule-associated protein RP/EB family member 3

1

1

High-throughput

0.479

High

1130805

RRP5
Protein RRP5 homolog

1

12

High-throughput

0.470

High

1383772

ARL8A
ADP-ribosylation factor-like protein 8A

1

0

High-throughput

0.458

High

422820

A4
Amyloid-beta precursor protein

1

2

Small-scale

0.445

High

61168

SSPO
SCO-spondin

1

1

Small-scale

0.439

High

246841

KDM1A
Lysine-specific histone demethylase 1A

1

5

High-throughput

0.437

High

643015

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

3

High-throughput

0.437

High

696154

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

878532

PAXI
Paxillin

1

1

High-throughput

0.437

High

941515

CTBP2
C-terminal-binding protein 2

1

3

High-throughput

0.437

High

1096782

RFA4
Replication protein A 30 kDa subunit

1

6

High-throughput

0.437

High

1137442

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.437

High

1155639

EZH2
Histone-lysine N-methyltransferase EZH2

1

12

High-throughput

0.437

High

1156569

CCDC6
Coiled-coil domain-containing protein 6

1

9

High-throughput

0.437

High

1158952

RBBP7
Histone-binding protein RBBP7

1

14

High-throughput

0.437

High

1178296

CL16A
Protein CLEC16A

1

2

High-throughput

0.437

High

1227213

A16L1
Autophagy-related protein 16-1

1

15

High-throughput

0.437

High

1229031

RNF43
E3 ubiquitin-protein ligase RNF43

1

9

High-throughput

0.437

High

1241924

FBX42
F-box only protein 42

1

9

High-throughput

0.437

High

1272655

DET1
DET1 homolog

1

3

High-throughput

0.437

High

1368925

GOGA1
Golgin subfamily A member 1

1

8

High-throughput

0.437

High

1383771

PF21A
PHD finger protein 21A

1

12

High-throughput

0.437

High

1383789

ZO2
Tight junction protein 2

1

7

High-throughput

0.437

High

1383791

RCOR1
REST corepressor 1

1

4

High-throughput

0.437

High

1383792

BRPF3
Bromodomain and PHD finger-containing protein 3

1

4

High-throughput

0.437

High

1383794

HECD1
E3 ubiquitin-protein ligase HECTD1

1

12

Small-scale

0.437

High

1383795

ALK
ALK tyrosine kinase receptor

1

11

High-throughput

0.437

High

244427

ZN862
Zinc finger protein 862

1

4

Small-scale

0.417

High

380115

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

1

High-throughput

0.407

High

1383778

ZDHC5
Palmitoyltransferase ZDHHC5

1

3

High-throughput

0.407

High

1013319

HTRA4
Serine protease HTRA4

2

0

High-throughput

0.328

High

847788

SSRB
Translocon-associated protein subunit beta

1

0

High-throughput

0.279

Low

1088784

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

0

High-throughput

0.279

Low

1306881

INLR1
Interferon lambda receptor 1

1

0

High-throughput

0.279

Low

1316044

TRM2A
tRNA

1

0

High-throughput

0.279

Low

1316540

MCLN2
Mucolipin-2

1

0

High-throughput

0.279

Low

1324839

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.279

Low

1383773

ORAI1
Calcium release-activated calcium channel protein 1

1

0

High-throughput

0.279

Low

1383779

SEM4C
Semaphorin-4C

1

0

High-throughput

0.279

Low

1383788

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

1383793

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.279

Low

1383797

LAMP3
Lysosome-associated membrane glycoprotein 3

1

0

High-throughput

0.279

Low

122536

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

0

High-throughput

0.249

Low

1383784

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.249

Low

1383775

S35E1
Solute carrier family 35 member E1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025