Protein: MK13
Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4)

Gene: MK13, MAPK13
Organism: Homo sapiens
Interactions: 115
UniProt ID: O15264

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0004707 - MAP kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

173865

MK12
Mitogen-activated protein kinase 12

4

20

High-throughput

0.903

High

60250

POTEF
POTE ankyrin domain family member F

3

7

High-throughput

0.848

High

173891

KPCD1
Serine/threonine-protein kinase D1

1

20

Small-scale

0.734

High

173814

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.691

High

173815

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.691

High

173834

FPR1
fMet-Leu-Phe receptor

1

4

Small-scale

0.691

High

173886

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

10

High-throughput

0.691

High

173894

KS6A2
Ribosomal protein S6 kinase alpha-2

1

20

High-throughput

0.691

High

173895

KS6A1
Ribosomal protein S6 kinase alpha-1

1

20

High-throughput

0.691

High

173896

CDC37
Hsp90 co-chaperone Cdc37

1

9

High-throughput

0.691

High

173828

ATF2
Cyclic AMP-dependent transcription factor ATF-2

3

20

Small-scale

0.655

High

173888

SQSTM
Sequestosome-1

1

9

Small-scale

0.647

High

173898

MAPK5
MAP kinase-activated protein kinase 5

1

20

Small-scale

0.647

High

173819

TAU
Microtubule-associated protein tau

2

17

Small-scale

0.629

High

173804

RASK
GTPase KRas

1

7

High-throughput

0.618

High

173861

TCPG
T-complex protein 1 subunit gamma

2

17

Small-scale

0.601

High

173864

TCPD
T-complex protein 1 subunit delta

2

15

Small-scale

0.601

High

173885

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

2

12

Small-scale

0.584

High

173816

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

11

Small-scale

0.575

High

173821

PABP1
Polyadenylate-binding protein 1

1

6

Small-scale

0.575

High

173825

PLST
Plastin-3

1

13

Small-scale

0.575

High

173827

ENPL
Endoplasmin

1

20

Small-scale

0.575

High

173833

NUCL
Nucleolin

1

5

Small-scale

0.575

High

173837

SFPQ
Splicing factor, proline- and glutamine-rich

1

11

Small-scale

0.575

High

173850

FUS
RNA-binding protein FUS

1

6

Small-scale

0.575

High

173875

RAN
GTP-binding nuclear protein Ran

1

2

Small-scale

0.575

High

173884

G3BP1
Ras GTPase-activating protein-binding protein 1

1

4

Small-scale

0.575

High

173893

NONO
Non-POU domain-containing octamer-binding protein

1

12

Small-scale

0.575

High

173901

TFG
Protein TFG

1

5

Small-scale

0.575

High

173902

RBP56
TATA-binding protein-associated factor 2N

1

4

Small-scale

0.575

High

173910

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

11

Small-scale

0.575

High

173909

FBW1A
F-box/WD repeat-containing protein 1A

1

13

Small-scale

0.552

High

173897

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.549

High

173866

DRG2
Developmentally-regulated GTP-binding protein 2

1

1

High-throughput

0.536

High

173851

GPX4
Phospholipid hydroperoxide glutathione peroxidase GPX4

1

0

High-throughput

0.518

High

173869

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

173887

SMAD4
Mothers against decapentaplegic homolog 4

1

6

High-throughput

0.508

High

173800

HTRA2
Serine protease HTRA2, mitochondrial

1

5

Small-scale

0.501

High

173805

MBP
Myelin basic protein

1

10

Small-scale

0.501

High

173808

A4
Amyloid-beta precursor protein

1

7

High-throughput

0.501

High

173872

FGF12
Fibroblast growth factor 12

1

1

Small-scale

0.501

High

173907

COHA1
Collagen alpha-1(XVII) chain

1

1

High-throughput

0.489

High

173829

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

173842

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

173854

STAT3
Signal transducer and activator of transcription 3

1

8

Small-scale

0.479

High

173867

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.479

High

173882

EP300
Histone acetyltransferase p300

1

15

Small-scale

0.479

High

136089

PDXK
Pyridoxal kinase

1

0

High-throughput

0.458

High

133769

DDX3X
ATP-dependent RNA helicase DDX3X

1

6

Small-scale

0.445

High

173799

SERA
D-3-phosphoglycerate dehydrogenase

1

4

Small-scale

0.445

High

173801

IF2P
Eukaryotic translation initiation factor 5B

1

8

Small-scale

0.445

High

173802

LDHA
L-lactate dehydrogenase A chain

1

9

Small-scale

0.445

High

173803

PGK1
Phosphoglycerate kinase 1

1

2

Small-scale

0.445

High

173806

ALDOA
Fructose-bisphosphate aldolase A

1

2

Small-scale

0.445

High

173807

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

5

Small-scale

0.445

High

173809

RLA2
Large ribosomal subunit protein P2

1

3

Small-scale

0.445

High

173810

ENOA
Alpha-enolase

1

3

Small-scale

0.445

High

173811

LDHB
L-lactate dehydrogenase B chain

1

9

Small-scale

0.445

High

173812

PROF1
Profilin-1

1

3

Small-scale

0.445

High

173813

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

4

Small-scale

0.445

High

173817

PARP1
Poly [ADP-ribose] polymerase 1

1

10

Small-scale

0.445

High

173818

H14
Histone H1.4

1

10

Small-scale

0.445

High

173820

BIP
Endoplasmic reticulum chaperone BiP

1

14

Small-scale

0.445

High

173822

KCRB
Creatine kinase B-type

1

1

Small-scale

0.445

High

173823

XRCC6
X-ray repair cross-complementing protein 6

1

2

Small-scale

0.445

High

173824

EF2
Elongation factor 2

1

7

Small-scale

0.445

High

173826

KPYM
Pyruvate kinase PKM

1

6

Small-scale

0.445

High

173830

CBR1
Carbonyl reductase [NADPH] 1

1

4

Small-scale

0.445

High

173831

H12
Histone H1.2

1

10

Small-scale

0.445

High

173832

PGAM1
Phosphoglycerate mutase 1

1

1

Small-scale

0.445

High

173835

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

1

Small-scale

0.445

High

173836

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

1

Small-scale

0.445

High

173838

RS3
Small ribosomal subunit protein uS3

1

2

Small-scale

0.445

High

173839

SAHH
Adenosylhomocysteinase

1

1

Small-scale

0.445

High

173840

EF1B
Elongation factor 1-beta

1

4

Small-scale

0.445

High

173841

ATPA
ATP synthase subunit alpha, mitochondrial

1

7

Small-scale

0.445

High

173844

EF1D
Elongation factor 1-delta

1

4

Small-scale

0.445

High

173845

MARCS
Myristoylated alanine-rich C-kinase substrate

1

4

Small-scale

0.445

High

173846

PRDX6
Peroxiredoxin-6

1

10

Small-scale

0.445

High

173847

PDIA3
Protein disulfide-isomerase A3

1

5

Small-scale

0.445

High

173848

1433B
14-3-3 protein beta/alpha

1

20

Small-scale

0.445

High

173849

STIP1
Stress-induced-phosphoprotein 1

1

5

Small-scale

0.445

High

173852

TAGL2
Transgelin-2

1

13

Small-scale

0.445

High

173853

TCPZ
T-complex protein 1 subunit zeta

1

16

Small-scale

0.445

High

173855

MDHM
Malate dehydrogenase, mitochondrial

1

9

Small-scale

0.445

High

173857

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

9

Small-scale

0.445

High

173858

TCPE
T-complex protein 1 subunit epsilon

1

18

Small-scale

0.445

High

173859

NASP
Nuclear autoantigenic sperm protein

1

3

Small-scale

0.445

High

173860

FAS
Fatty acid synthase

1

4

Small-scale

0.445

High

173862

GDIB
Rab GDP dissociation inhibitor beta

1

1

Small-scale

0.445

High

173863

TCPQ
T-complex protein 1 subunit theta

1

20

Small-scale

0.445

High

173870

IF4A1
Eukaryotic initiation factor 4A-I

1

10

Small-scale

0.445

High

173873

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

11

Small-scale

0.445

High

173874

RS14
Small ribosomal subunit protein uS11

1

2

Small-scale

0.445

High

173876

1433Z
14-3-3 protein zeta/delta

1

20

Small-scale

0.445

High

173877

YBOX1
Y-box-binding protein 1

1

4

Small-scale

0.445

High

173878

EF1A1
Elongation factor 1-alpha 1

1

6

Small-scale

0.445

High

173879

TCPB
T-complex protein 1 subunit beta

1

18

Small-scale

0.445

High

173880

CLH1
Clathrin heavy chain 1

1

2

Small-scale

0.445

High

173881

DHX9
ATP-dependent RNA helicase A

1

2

Small-scale

0.445

High

173883

ILF3
Interleukin enhancer-binding factor 3

1

5

Small-scale

0.445

High

173890

PDIA6
Protein disulfide-isomerase A6

1

5

Small-scale

0.445

High

173900

DDX1
ATP-dependent RNA helicase DDX1

1

11

Small-scale

0.445

High

173904

NP1L4
Nucleosome assembly protein 1-like 4

1

3

Small-scale

0.445

High

173905

CYBP
Calcyclin-binding protein

1

1

Small-scale

0.445

High

173856

LAP2A
Lamina-associated polypeptide 2, isoform alpha

1

0

Small-scale

0.426

High

173892

IPYR
Inorganic pyrophosphatase

1

0

Small-scale

0.426

High

173899

SERB1
SERPINE1 mRNA-binding protein 1

1

0

Small-scale

0.426

High

173908

NUDC
Nuclear migration protein nudC

1

0

Small-scale

0.426

High

173843

CALX
Calnexin

1

2

Small-scale

0.407

High

173871

ARF3
ADP-ribosylation factor 3

1

3

Small-scale

0.407

High

173889

GANAB
Neutral alpha-glucosidase AB

1

5

Small-scale

0.407

High

173903

EFGM
Elongation factor G, mitochondrial

1

7

Small-scale

0.407

High

173906

AKIP1
A-kinase-interacting protein 1

1

0

High-throughput

0.265

Low

173868

ATP5I
ATP synthase subunit e, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024