HitPredict

Interactor 1: HBB1 (P02091)
Hemoglobin subunit beta-1 (Beta-1-globin) (Hemoglobin beta chain, major-form) (Hemoglobin beta-1 chain)
Gene: Hbb

Interactor 2: INSR (P15127)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Species: Rattus norvegicus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	30300385
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0044877 - protein-containing complex binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 147 Rn			1 1383
+	Rn
		355077 HBA_RAT (4-146): 1.53e-46: 149: 35.17		INSR_RAT (1-1383): 0: 1575: 100.00
+	Hs
		355146 HBD_HUMAN (1-147): 2.08e-68: 205: 80.95		MERTK_HUMAN (810-1302): 3.9e-61: 230: 31.54
+	Hs
		936100 HBA_HUMAN (4-146): 1.88e-49: 157: 40.69		ALK_HUMAN (997-1340): 6.12e-71: 264: 41.57
+	Hs
		355091 HBAZ_HUMAN (4-146): 3.99e-52: 163: 37.24		FGFR3_HUMAN (1016-1288): 2.88e-60: 224: 40.07
+	Hs
		936034 HBA_HUMAN (4-146): 1.88e-49: 157: 40.69		MERTK_HUMAN (810-1302): 3.9e-61: 230: 31.54
+	Hs
		355132 HBD_HUMAN (1-147): 2.08e-68: 205: 80.95		ERBB3_HUMAN (5-368): 5.74e-31: 135: 19.70
+	Hs
		601886 HBG2_HUMAN (1-147): 9.95e-68: 203: 72.79		ERBB3_HUMAN (5-368): 5.74e-31: 135: 19.70
+	Hs
		601884 HBB_HUMAN (1-147): 1.84e-67: 202: 81.63		ERBB3_HUMAN (5-368): 5.74e-31: 135: 19.70
+	Hs
		355197 HBE_HUMAN (1-147): 1.06e-66: 200: 72.79		ERBB3_HUMAN (5-368): 5.74e-31: 135: 19.70
+	Hs
		601885 HBG1_HUMAN (1-147): 1.72e-66: 200: 72.11		ERBB3_HUMAN (5-368): 5.74e-31: 135: 19.70
+	Hs
		601887 HBA_HUMAN (4-146): 1.88e-49: 157: 40.69		ERBB3_HUMAN (5-368): 5.74e-31: 135: 19.70
+	Hs
		338269 HBA_HUMAN (4-146): 1.88e-49: 157: 40.69		EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50