HitPredict

Interactor 1: H2B (P02283)
Histone H2B
Gene: H2B, His2B;

Interactor 2: PCL (Q24459)
Polycomb protein Pcl (Polycomblike protein)
Gene: PCL

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	17762866
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 123 Dm			1 1043
+	Hs
		918789 H2B1C_HUMAN (3-123): 1.51e-48: 153: 81.30		MTF2_HUMAN (344-824): 8.83e-112: 360: 25.45
+	Hs
		707777 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		ASH2L_HUMAN (475-776): 1.75e-55: 206: 14.37
+	Hs
		918749 H2B1C_HUMAN (3-123): 1.51e-48: 153: 81.30		ASH2L_HUMAN (475-776): 1.75e-55: 206: 14.37
+	Hs
		918772 H2B1C_HUMAN (3-123): 1.51e-48: 153: 81.30		KMT2B_HUMAN (269-600): 8.48e-38: 156: 14.45
+	Hs
		1059777 H2B1H_HUMAN (3-123): 5.28e-49: 154: 81.30		CHD4_HUMAN (409-579): 2.55e-34: 145: 18.08
+	Hs
		707596 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		KMT2A_HUMAN (184-601): 1.2e-34: 146: 12.04
+	Hs
		918303 H2B1C_HUMAN (3-123): 1.51e-48: 153: 81.30		KMT2A_HUMAN (184-601): 1.2e-34: 146: 12.04
+	Hs
		975269 H2B2E_HUMAN (3-123): 9.53e-49: 153: 82.11		KMT2A_HUMAN (184-601): 1.2e-34: 146: 12.04
+	Hs
		707635 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		CHD4_HUMAN (409-579): 2.55e-34: 145: 18.08
+	Hs
		918368 H2B1C_HUMAN (3-123): 1.51e-48: 153: 81.30		CHD4_HUMAN (409-579): 2.55e-34: 145: 18.08
+	Hs
		918541 H2B1C_HUMAN (3-123): 1.51e-48: 153: 81.30		CHD5_HUMAN (414-578): 5.28e-31: 134: 15.98
+	Hs
		707663 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		SRCAP_HUMAN (22-354): 2.46e-10: 67.2: 17.22
+	Hs
		918462 H2B1C_HUMAN (3-123): 1.51e-48: 153: 81.30		SRCAP_HUMAN (22-354): 2.46e-10: 67.2: 17.22
+	Hs
		152598 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		KMT2D_HUMAN (2-408): 2.68e-09: 63.9: 11.33
+	Hs
		1056919 H2B1H_HUMAN (3-123): 5.28e-49: 154: 81.30		MDC1_HUMAN (24-346): 5.69e-09: 62.6: 19.95
+	Hs
		707690 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		KMT2C_HUMAN (2-445): 3.31e-09: 63.5: 11.59
+	Hs
		918533 H2B1C_HUMAN (3-123): 1.51e-48: 153: 81.30		KMT2C_HUMAN (2-445): 3.31e-09: 63.5: 11.59
+	Hs
		1056847 H2B2E_HUMAN (3-123): 9.53e-49: 153: 82.11		MDC1_HUMAN (24-346): 5.69e-09: 62.6: 19.95
+	Hs
		707631 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		MDC1_HUMAN (24-346): 5.69e-09: 62.6: 19.95
+	Hs
		918364 H2B1C_HUMAN (3-123): 1.51e-48: 153: 81.30		MDC1_HUMAN (24-346): 5.69e-09: 62.6: 19.95