HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: RPC1 (P04051)
DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (RNA polymerase III subunit C160)
Gene: RPO31

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	16429126, 22199229
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 1460
+	Sc
		355718 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		RPC1_YEAST (1-1460): 0: 1720: 100.00
+	Hs
		624917 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		RPB1_HUMAN (6-1435): 0: 1537: 32.05
+	Hs
		624984 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		RPB1_HUMAN (6-1435): 0: 1537: 32.05
+	Hs
		241452 H2B1K_HUMAN (7-128): 1.06e-45: 146: 70.16		RPB1_HUMAN (6-1435): 0: 1537: 32.05
+	Hs
		420805 H2B1J_HUMAN (7-128): 5.77e-46: 146: 70.16		RPB1_HUMAN (6-1435): 0: 1537: 32.05
+	Hs
		624851 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		RPB1_HUMAN (6-1435): 0: 1537: 32.05
+	Hs
		624835 H2B1D_HUMAN (7-128): 1.99e-45: 145: 70.16		RPB1_HUMAN (6-1435): 0: 1537: 32.05
+	Hs
		625015 H2B1L_HUMAN (7-128): 2.46e-44: 142: 70.16		RPB1_HUMAN (6-1435): 0: 1537: 32.05
+	Sc
		355717 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		RPB1_YEAST (1-1435): 0: 1445: 32.14
+	Sc
		355285 H2B1_YEAST (1-131): 2.54e-44: 143: 100.00		RPB1_YEAST (1-1435): 0: 1445: 32.14
+	Hs
		317082 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		RPA1_HUMAN (1257-1432): 1.36e-47: 189: 27.62