HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: UBC2 (P06104)
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Radiation sensitivity protein 6) (Ubiquitin carrier protein UBC2) (Ubiquitin-protein ligase UBC2)
Gene: RAD6

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.721

Property	Details
Experiments	10642555, 36715322, 37633270, 37794081, 37923031
Identification Methods	coimmunoprecipitation, enzymatic study, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 172
+	Sc
		355730 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		UBC2_YEAST (1-150): 1.23e-78: 232: 100.00
+	Mm
		1145473 H2B2B_MOUSE (7-128): 7.21e-47: 149: 70.97		UBE2A_MOUSE (1-151): 9.07e-74: 220: 69.54
+	Hs
		829009 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBE2A_HUMAN (1-151): 9.07e-74: 220: 69.54
+	Hs
		707552 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBE2A_HUMAN (1-151): 9.07e-74: 220: 69.54
+	Hs
		828971 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		UBE2A_HUMAN (1-151): 9.07e-74: 220: 69.54
+	Mm
		927791 H2B2B_MOUSE (7-128): 7.21e-47: 149: 70.97		UBE2B_MOUSE (1-151): 7.03e-73: 217: 69.54
+	Hs
		828968 H2B1D_HUMAN (7-128): 1.99e-45: 145: 70.16		UBE2A_HUMAN (1-151): 9.07e-74: 220: 69.54
+	Hs
		927767 H2B1A_HUMAN (29-128): 2.91e-32: 112: 80.00		UBE2B_HUMAN (1-151): 7.03e-73: 217: 69.54