Protein: EPC1
Enhancer of polycomb homolog 1

Gene: EPC1
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q9H2F5

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000724 - double-strand break repair via homologous recombination
GO:0000786 - nucleosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1371286

KAT5
Histone acetyltransferase KAT5

10

7

Small-scale

0.975

High

1431819

ING3
Inhibitor of growth protein 3

5

5

Small-scale

0.925

High

1431820

MO4L1
Mortality factor 4-like protein 1

9

5

Small-scale

0.751

High

1136856

MO4L2
Mortality factor 4-like protein 2

7

5

Small-scale

0.745

High

1431817

MRGBP
MRG/MORF4L-binding protein

7

1

Small-scale

0.744

High

1431823

RUVB2
RuvB-like 2

6

6

Small-scale

0.734

High

340404

YETS4
YEATS domain-containing protein 4

5

3

Small-scale

0.722

High

1431813

EAF6
Chromatin modification-related protein MEAF6

5

2

Small-scale

0.716

High

1431815

DMAP1
DNA methyltransferase 1-associated protein 1

5

7

Small-scale

0.716

High

1431824

RUVB1
RuvB-like 1

5

6

Small-scale

0.714

High

1244939

FOXR1
Forkhead box protein R1

4

3

High-throughput

0.699

High

373125

MYC
Myc proto-oncogene protein

5

7

High-throughput

0.699

High

1361579

ING5
Inhibitor of growth protein 5

1

5

High-throughput

0.691

High

502124

H2AZ
Histone H2A.Z

4

2

Small-scale

0.691

High

1381859

H2B1A
Histone H2B type 1-A

4

7

High-throughput

0.691

High

553764

MYCL
Protein L-Myc

3

7

Small-scale

0.667

High

1245360

FOXR2
Forkhead box protein R2

3

3

High-throughput

0.667

High

1431825

TRRAP
Transformation/transcription domain-associated protein

3

3

Small-scale

0.667

High

1291981

JAZF1
Juxtaposed with another zinc finger protein 1

3

2

Small-scale

0.656

High

1429933

BRD8
Bromodomain-containing protein 8

3

3

Small-scale

0.656

High

1155327

VPS72
Vacuolar protein sorting-associated protein 72 homolog

3

1

Small-scale

0.650

High

1053310

MBTD1
MBT domain-containing protein 1

2

1

Small-scale

0.639

High

959654

MAX
Protein max

2

7

Small-scale

0.611

High

1396742

EP400
E1A-binding protein p400

2

2

Small-scale

0.611

High

1431814

PLAC1
Placenta-specific protein 1

3

1

High-throughput

0.609

High

282783

E2F6
Transcription factor E2F6

2

1

Small-scale

0.606

High

911374

IMA5
Importin subunit alpha-5

2

1

High-throughput

0.601

High

1405730

KLF6
Krueppel-like factor 6

2

10

High-throughput

0.584

High

572209

TRI27
Zinc finger protein RFP

1

1

Small-scale

0.552

High

1409746

HOP
Homeodomain-only protein

1

0

Small-scale

0.549

High

618111

K1C15
Keratin, type I cytoskeletal 15

1

0

High-throughput

0.549

High

355294

ACL6A
Actin-like protein 6A

1

3

Small-scale

0.536

High

729451

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

1

High-throughput

0.536

High

833776

KDM5C
Lysine-specific demethylase 5C

1

1

High-throughput

0.536

High

953096

ACTB
Actin, cytoplasmic 1

1

2

Small-scale

0.536

High

1323980

H2B3B
Histone H2B type 3-B

1

8

High-throughput

0.536

High

1155757

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

Small-scale

0.529

High

210113

CRX
Cone-rod homeobox protein

1

1

High-throughput

0.479

High

339852

KLF8
Krueppel-like factor 8

1

10

High-throughput

0.479

High

474280

NFIC
Nuclear factor 1 C-type

1

2

High-throughput

0.479

High

520366

ANDR
Androgen receptor

1

4

High-throughput

0.479

High

549348

SRF
Serum response factor

1

1

Small-scale

0.479

High

739029

ELF1
ETS-related transcription factor Elf-1

1

3

High-throughput

0.479

High

834051

HNF4A
Hepatocyte nuclear factor 4-alpha

1

3

High-throughput

0.479

High

944738

KLF3
Krueppel-like factor 3

1

10

High-throughput

0.479

High

980311

H4
Histone H4

1

2

High-throughput

0.479

High

981086

H2B1C
Histone H2B type 1-C/E/F/G/I

1

8

High-throughput

0.479

High

1029151

E2F1
Transcription factor E2F1

1

1

High-throughput

0.479

High

1088008

NFIA
Nuclear factor 1 A-type

1

1

High-throughput

0.479

High

1118776

KLF5
Krueppel-like factor 5

1

10

High-throughput

0.479

High

1152740

ELF2
ETS-related transcription factor Elf-2

1

3

High-throughput

0.479

High

1351156

SP7
Transcription factor Sp7

1

9

High-throughput

0.479

High

1367251

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

1405635

ELF4
ETS-related transcription factor Elf-4

1

3

High-throughput

0.479

High

1416905

KLF16
Krueppel-like factor 16

1

8

High-throughput

0.479

High

1431821

KLF15
Krueppel-like factor 15

1

10

High-throughput

0.479

High

1431822

MED23
Mediator of RNA polymerase II transcription subunit 23

1

1

High-throughput

0.479

High

1431826

KLF12
Krueppel-like factor 12

1

10

High-throughput

0.479

High

285471

EED
Polycomb protein EED

1

0

Small-scale

0.458

High

378521

IL1A
Interleukin-1 alpha

1

0

Small-scale

0.458

High

538469

EGR2
E3 SUMO-protein ligase EGR2

1

0

High-throughput

0.458

High

775910

HNF1B
Hepatocyte nuclear factor 1-beta

1

0

High-throughput

0.458

High

994373

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

0

Small-scale

0.458

High

1338954

NUP43
Nucleoporin Nup43

1

0

High-throughput

0.458

High

1431816

MDN1
Midasin

1

0

High-throughput

0.458

High

1398358

CEP63
Centrosomal protein of 63 kDa

1

1

High-throughput

0.457

High

1413611

AN32E
Acidic leucine-rich nuclear phosphoprotein 32 family member E

1

1

Small-scale

0.445

High

1431818

EXOC1
Exocyst complex component 1

1

0

High-throughput

0.438

High

71819

FOXO6
Forkhead box protein O6

1

0

High-throughput

0.426

High

239205

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.426

High

1316986

FAM9B
Protein FAM9B

1

0

High-throughput

0.426

High

1335717

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.407

High

1238600

RINT1
RAD50-interacting protein 1

2

0

High-throughput

0.330

High

477175

ACM5
Muscarinic acetylcholine receptor M5

1

0

High-throughput

0.282

High

1351825

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.279

Low

70848

SYC1L
Synaptonemal complex central element protein 1-like

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025