HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: RPB3 (P16370)
DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (B44.5) (DNA-directed RNA polymerase II 45 kDa polypeptide)
Gene: RPB3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	33888559, 37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 318
+	Sc
		355765 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		RPB3_YEAST (1-318): 3.91e-173: 484: 100.00
+	Hs
		583488 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		RPB3_HUMAN (6-270): 4.25e-119: 345: 45.19
+	Sc
		355739 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		RPAC1_YEAST (3-258): 3.25e-89: 271: 23.31
+	Sc
		355303 H2B1_YEAST (1-131): 2.54e-44: 143: 100.00		RPAC1_YEAST (3-258): 3.25e-89: 271: 23.31