HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: NAP1 (P25293)
Nucleosome assembly protein
Gene: NAP1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	1.00	0.963

Property	Details
Experiments	12928440, 28468903, 31062022, 11309407, 16554755, 16429126, 37968396, 22199229
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 417
+	Sc
		355792 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		NAP1_YEAST (1-417): 1.02e-132: 389: 100.00
+	Hs
		876805 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		NP1L1_HUMAN (23-416): 7.68e-117: 348: 31.75
+	Hs
		707565 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		NP1L1_HUMAN (23-416): 7.68e-117: 348: 31.75
+	Hs
		876745 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		NP1L1_HUMAN (23-416): 7.68e-117: 348: 31.75
+	Hs
		1087365 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		NP1L4_HUMAN (41-371): 1.85e-116: 346: 33.82
+	Hs
		420873 H2B1J_HUMAN (7-128): 5.77e-46: 146: 70.16		NP1L4_HUMAN (41-371): 1.85e-116: 346: 33.82
+	Hs
		707727 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		NP1L4_HUMAN (41-371): 1.85e-116: 346: 33.82
+	Hs
		876845 H2B3B_HUMAN (7-128): 2.3e-44: 143: 64.52		NP1L1_HUMAN (23-416): 7.68e-117: 348: 31.75
+	Hs
		1231232 H2B3B_HUMAN (7-128): 2.3e-44: 143: 64.52		NP1L4_HUMAN (41-371): 1.85e-116: 346: 33.82
+	Hs
		876869 H2B1A_HUMAN (29-128): 2.91e-32: 112: 80.00		NP1L1_HUMAN (23-416): 7.68e-117: 348: 31.75
+	Hs
		1282951 H2B1A_HUMAN (29-128): 2.91e-32: 112: 80.00		NP1L4_HUMAN (41-371): 1.85e-116: 346: 33.82
+	Dm
		355262 H2B_DROME (8-128): 2.21e-45: 145: 67.77		Q24150_DROME (84-365): 1.94e-98: 300: 32.06
+	Dm
		355275 H2B_DROME (8-128): 2.21e-45: 145: 67.77		Q9W1G7_DROME (84-365): 2.07e-98: 300: 32.06
+	Ce
		380429 H2B1_CAEEL (9-128): 2.33e-47: 150: 72.50		Q19007_CAEEL (69-387): 6.48e-86: 266: 29.54
+	Ce
		1090450 H2B2_CAEEL (8-128): 4.15e-47: 149: 71.90		Q19007_CAEEL (69-387): 6.48e-86: 266: 29.54
+	Hs
		707676 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		TSYL5_HUMAN (21-361): 6.27e-65: 215: 14.58
+	Hs
		707747 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		TSYL1_HUMAN (139-361): 9.24e-63: 210: 18.83
+	Hs
		886086 H2B1D_HUMAN (7-128): 1.99e-45: 145: 70.16		SET_HUMAN (133-361): 5.71e-57: 190: 20.96
+	Hs
		963873 H2B1A_HUMAN (29-128): 2.91e-32: 112: 80.00		SET_HUMAN (133-361): 5.71e-57: 190: 20.96