Protein: CLN3
Battenin (Batten disease protein) (Protein CLN3)

Gene: CLN3
Organism: Homo sapiens
Interactions: 121
UniProt ID: Q13286

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001508 - action potential
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005764 - lysosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

172772

XPO1
Exportin-1

2

2

Small-scale

0.611

High

1040117

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

2

6

Small-scale

0.611

High

1101163

ECM29
Proteasome adapter and scaffold protein ECM29

2

2

Small-scale

0.611

High

1101181

GCN1
Stalled ribosome sensor GCN1

2

2

Small-scale

0.611

High

1101198

DIC
Mitochondrial dicarboxylate carrier

2

5

Small-scale

0.611

High

418099

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

0

Small-scale

0.585

High

1008125

PRKDC
DNA-dependent protein kinase catalytic subunit

2

0

Small-scale

0.585

High

1101158

MIC60
MICOS complex subunit MIC60

2

0

Small-scale

0.585

High

1101159

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

2

0

Small-scale

0.585

High

1101165

ARMC6
Armadillo repeat-containing protein 6

2

0

Small-scale

0.585

High

1101182

NU205
Nuclear pore complex protein Nup205

2

0

Small-scale

0.585

High

1101207

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

2

0

Small-scale

0.585

High

813075

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

2

0

Small-scale

0.559

High

895238

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

2

0

Small-scale

0.559

High

1101191

GHC1
Mitochondrial glutamate carrier 1

2

5

Small-scale

0.558

High

210387

MTLR
Motilin receptor

1

1

High-throughput

0.536

High

220904

XPOT
Exportin-T

1

2

High-throughput

0.536

High

355362

B3GT4
Beta-1,3-galactosyltransferase 4

1

1

High-throughput

0.536

High

640383

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

1

High-throughput

0.536

High

720605

GRPR
Gastrin-releasing peptide receptor

1

1

High-throughput

0.536

High

833816

P2RY2
P2Y purinoceptor 2

1

1

High-throughput

0.536

High

835268

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

3

High-throughput

0.536

High

867957

GLR
Glucagon receptor

1

3

High-throughput

0.536

High

1101202

CSEN
Calsenilin

1

0

Small-scale

0.529

High

48617

ESYT2
Extended synaptotagmin-2

1

0

High-throughput

0.513

High

125439

LEG9
Galectin-9

1

0

High-throughput

0.513

High

178549

PLCB
1-acyl-sn-glycerol-3-phosphate acyltransferase beta

1

0

High-throughput

0.513

High

334180

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

0

High-throughput

0.513

High

469479

SYPH
Synaptophysin

1

0

High-throughput

0.513

High

471647

CY1
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.513

High

701808

ABCD3
ATP-binding cassette sub-family D member 3

1

0

High-throughput

0.513

High

766518

PHB1
Prohibitin 1

1

0

High-throughput

0.513

High

820553

GPV
Platelet glycoprotein V

1

0

High-throughput

0.513

High

832399

OPRX
Nociceptin receptor

1

0

High-throughput

0.513

High

852742

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

0

High-throughput

0.513

High

905557

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.513

High

938560

PSA
Puromycin-sensitive aminopeptidase

1

0

High-throughput

0.513

High

944462

GEMI4
Gem-associated protein 4

1

0

High-throughput

0.513

High

1101156

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.513

High

1101157

PCH2
Pachytene checkpoint protein 2 homolog

1

0

High-throughput

0.513

High

1101162

RIF1
Telomere-associated protein RIF1

1

0

High-throughput

0.513

High

1101169

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.513

High

1101171

TPRA1
Transmembrane protein adipocyte-associated 1

1

0

High-throughput

0.513

High

1101174

NUP93
Nuclear pore complex protein Nup93

1

0

High-throughput

0.513

High

1101175

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

1101179

GLMP
Glycosylated lysosomal membrane protein

1

0

High-throughput

0.513

High

1101183

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

1101184

OPALI
Opalin

1

0

High-throughput

0.513

High

1101185

SGMR1
Sigma non-opioid intracellular receptor 1

1

0

High-throughput

0.513

High

1101186

FUCO2
Plasma alpha-L-fucosidase

1

0

High-throughput

0.513

High

1101190

UN45A
Protein unc-45 homolog A

1

0

High-throughput

0.513

High

1101195

FANCI
Fanconi anemia group I protein

1

0

High-throughput

0.513

High

1101200

DDX20
Probable ATP-dependent RNA helicase DDX20

1

0

High-throughput

0.513

High

1101204

TELO2
Telomere length regulation protein TEL2 homolog

1

0

High-throughput

0.513

High

1101205

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.513

High

284394

CLN5
Bis(monoacylglycero)phosphate synthase CLN5

1

0

Small-scale

0.493

High

1101167

CDHR3
Cadherin-related family member 3

1

0

High-throughput

0.493

High

1101173

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.493

High

1101176

MAGB6
Melanoma-associated antigen B6

1

0

High-throughput

0.493

High

1101166

SFXN4
Sideroflexin-4

1

2

High-throughput

0.489

High

1101193

S61A2
Protein transport protein Sec61 subunit alpha isoform 2

1

1

High-throughput

0.489

High

1101203

SBDS
Ribosome maturation protein SBDS

1

1

Small-scale

0.481

High

229185

B3GT2
Beta-1,3-galactosyltransferase 2

1

1

High-throughput

0.479

High

229705

CALU
Calumenin

1

1

Small-scale

0.479

High

321233

ERLN2
Erlin-2

1

1

Small-scale

0.479

High

420517

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

1

Small-scale

0.479

High

424883

ADT2
ADP/ATP translocase 2

1

3

Small-scale

0.479

High

552003

ADT1
ADP/ATP translocase 1

1

3

Small-scale

0.479

High

552223

ADT3
ADP/ATP translocase 3

1

3

Small-scale

0.479

High

598074

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

1

Small-scale

0.479

High

612213

ARF4
ADP-ribosylation factor 4

1

2

Small-scale

0.479

High

916248

TXTP
Tricarboxylate transport protein, mitochondrial

1

5

Small-scale

0.479

High

934065

XPO2
Exportin-2

1

1

Small-scale

0.479

High

958765

ARF3
ADP-ribosylation factor 3

1

2

Small-scale

0.479

High

963056

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

1

Small-scale

0.479

High

1015012

ARF5
ADP-ribosylation factor 5

1

2

Small-scale

0.479

High

1024344

S25A3
Solute carrier family 25 member 3

1

4

Small-scale

0.479

High

1042739

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

3

High-throughput

0.479

High

1101154

RCN2
Reticulocalbin-2

1

1

Small-scale

0.479

High

1101170

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.479

High

1101180

LGAT1
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1

1

1

Small-scale

0.479

High

1101194

XPO5
Exportin-5

1

3

Small-scale

0.479

High

1101201

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

4

Small-scale

0.479

High

50547

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.458

High

178257

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

209551

SERA
D-3-phosphoglycerate dehydrogenase

1

0

Small-scale

0.458

High

255623

DPM1
Dolichol-phosphate mannosyltransferase subunit 1

1

0

Small-scale

0.458

High

338613

AGRL2
Adhesion G protein-coupled receptor L2

1

0

Small-scale

0.458

High

341417

CDS2
Phosphatidate cytidylyltransferase 2

1

0

Small-scale

0.458

High

350232

FADS2
Acyl-CoA 6-desaturase

1

0

Small-scale

0.458

High

390559

TFR1
Transferrin receptor protein 1

1

0

Small-scale

0.458

High

417410

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

Small-scale

0.458

High

479601

DOPO
Dopamine beta-hydroxylase

1

0

Small-scale

0.458

High

837596

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

894720

EMD
Emerin

1

0

Small-scale

0.458

High

903685

SSRD
Translocon-associated protein subunit delta

1

0

Small-scale

0.458

High

944247

TMM33
Transmembrane protein 33

1

0

Small-scale

0.458

High

1058399

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.458

High

1101153

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1101155

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

Small-scale

0.458

High

1101177

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

0

Small-scale

0.458

High

1101178

FACR1
Fatty acyl-CoA reductase 1

1

0

Small-scale

0.458

High

1101188

STRA6
Receptor for retinol uptake STRA6

1

0

Small-scale

0.458

High

1101189

ZY11B
Protein zyg-11 homolog B

1

0

High-throughput

0.458

High

1101196

TECR
Very-long-chain enoyl-CoA reductase

1

0

Small-scale

0.458

High

1101197

HACD3
Very-long-chain

1

0

Small-scale

0.458

High

1101206

SAM50
Sorting and assembly machinery component 50 homolog

1

0

Small-scale

0.458

High

1101187

SFXN3
Sideroflexin-3

1

2

Small-scale

0.437

High

1101192

SFXN1
Sideroflexin-1

1

2

Small-scale

0.437

High

380021

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.426

High

1101152

CLN3
Battenin

1

0

High-throughput

0.426

High

1101160

KLH22
Kelch-like protein 22

1

0

High-throughput

0.426

High

1101168

COX15
Heme A synthase COX15

2

0

Small-scale

0.318

High

1101172

S22A9
Organic anion transporter 7

1

0

High-throughput

0.279

Low

165574

SCAM3
Secretory carrier-associated membrane protein 3

1

0

Small-scale

0.249

Low

299645

ATP5L
ATP synthase F(0) complex subunit g, mitochondrial

1

0

Small-scale

0.249

Low

651793

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

0

Small-scale

0.249

Low

1101161

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

0

High-throughput

0.249

Low

1101164

MIC13
MICOS complex subunit MIC13

1

0

Small-scale

0.249

Low

1101199

DYH17
Dynein axonemal heavy chain 17

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025