HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: SMC1 (P32908)
Structural maintenance of chromosomes protein 1 (DA-box protein SMC1)
Gene: SMC1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21179020
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 1225
+	Hs
		1057346 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		SMC1A_HUMAN (1-1225): 2.94e-92: 325: 26.86
+	Hs
		707632 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		SMC1A_HUMAN (1-1225): 2.94e-92: 325: 26.86
+	Hs
		1087272 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		SMC1B_HUMAN (1-1225): 1.31e-86: 309: 24.60
+	Hs
		311555 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		SMC2_HUMAN (3-1217): 6.93e-75: 273: 18.17
+	Sc
		355483 H2B1_YEAST (1-131): 2.54e-44: 143: 100.00		SMC2_YEAST (3-1216): 3.11e-76: 277: 16.23
+	Hs
		1274480 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		SMC3_HUMAN (3-1222): 4.26e-74: 271: 16.89
+	Hs
		241662 H2B1K_HUMAN (7-128): 1.06e-45: 146: 70.16		SMC3_HUMAN (3-1222): 4.26e-74: 271: 16.89
+	Hs
		420896 H2B1J_HUMAN (7-128): 5.77e-46: 146: 70.16		SMC3_HUMAN (3-1222): 4.26e-74: 271: 16.89
+	Hs
		918774 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		SMC3_HUMAN (3-1222): 4.26e-74: 271: 16.89
+	Sc
		355931 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		SMC3_YEAST (3-1221): 2.09e-67: 251: 15.88
+	Sc
		355537 H2B1_YEAST (1-131): 2.54e-44: 143: 100.00		SMC3_YEAST (3-1221): 2.09e-67: 251: 15.88
+	Hs
		1274476 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		MYH2_HUMAN (484-1130): 7.06e-20: 98.6: 8.59