HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: SWC5 (P38326)
SWR1-complex protein 5
Gene: SWC5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.689

Property	Details
Experiments	37968396, 33320380, 38809771, 21179020
Identification Methods	affinity chromatography technology, pull down, fluorescent resonance energy transfer, x-ray crystallography, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 303
+	Sc
		355881 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		SWC5_YEAST (1-303): 2.4e-101: 300: 100.00
+	Hs
		1087456 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		CFDP1_HUMAN (82-292): 7.23e-46: 158: 25.82
+	Hs
		1274465 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		CFDP1_HUMAN (82-292): 7.23e-46: 158: 25.82
+	Hs
		420892 H2B1J_HUMAN (7-128): 5.77e-46: 146: 70.16		CFDP1_HUMAN (82-292): 7.23e-46: 158: 25.82
+	Hs
		918751 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		CFDP1_HUMAN (82-292): 7.23e-46: 158: 25.82
+	Hs
		1231258 H2B3B_HUMAN (7-128): 2.3e-44: 143: 64.52		CFDP1_HUMAN (82-292): 7.23e-46: 158: 25.82
+	Hs
		1282977 H2B1A_HUMAN (29-128): 2.91e-32: 112: 80.00		CFDP1_HUMAN (82-292): 7.23e-46: 158: 25.82