HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: SPT16 (P32558)
FACT complex subunit SPT16 (Cell division control protein 68) (Facilitates chromatin transcription complex subunit SPT16) (Suppressor of Ty protein 16)
Gene: SPT16

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.970

Property	Details
Experiments	23499444, 26804921, 27143358, 16429126, 33963860, 37968396, 37850662, 16554755, 22199229, 21179020
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	CENP-T_C~Rtt106
Common GO terms	GO:0006325 - chromatin organization GO:0006334 - nucleosome assembly GO:0031298 - replication fork protection complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 1035
+	Hs
		918210 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		SP16H_HUMAN (4-1028): 0: 1082: 32.76
+	Sp
		292838 H4_SCHPO (18-103): 2.79e-41: 133: 90.70		SPT16_SCHPO (1-1032): 0: 1047: 45.64
+	Sc
		356547 H4_YEAST (1-103): 5.28e-47: 147: 100.00		YFH6_YEAST (5-446): 1.17e-54: 201: 12.85