HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: BDF1 (P35817)
Bromodomain-containing factor 1
Gene: BDF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.751

Property	Details
Experiments	12620224, 28068333, 17049045, 34056863, 37968396, 14761951, 11343701, 14690608, 22199229
Identification Methods	pull down, affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 103 Sc			1 686
+	Sp
		448927 H4_SCHPO (18-103): 2.79e-41: 133: 90.70		YK82_SCHPO (6-672): 2.66e-107: 343: 24.89
+	Hs
		917466 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		BRWD3_HUMAN (103-567): 1.39e-64: 235: 14.96
+	Dm
		950390 H4_DROME (18-103): 2.42e-41: 133: 90.70		Q4V5A7_DROME (123-684): 1.91e-64: 227: 13.88
+	Hs
		600119 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		TAF1_HUMAN (103-657): 6.62e-61: 223: 12.18
+	Hs
		917979 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		BRD7_HUMAN (14-550): 1.39e-59: 213: 14.46
+	Sc
		356667 H4_YEAST (1-103): 5.28e-47: 147: 100.00		RSC4_YEAST (105-686): 4.92e-54: 198: 15.22
+	Hs
		917576 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		TAF1L_HUMAN (115-578): 3.56e-52: 197: 14.62
+	Hs
		917517 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		PB1_HUMAN (91-664): 4.19e-38: 154: 11.97
+	Hs
		917684 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CBP_HUMAN (249-418): 7.85e-37: 150: 25.73
+	Zm
		19319 A0A1D6IAU4_MAIZE (18-103): 9.75e-45: 142: 89.54		A0A1D6HCG5_MAIZE (143-321): 6.05e-31: 131: 26.26
+	Sc
		356752 H4_YEAST (1-103): 5.28e-47: 147: 100.00		BDF2_YEAST (17-331): 4.8e-28: 121: 16.35
+	Mm
		918262 H4_MOUSE (18-103): 1.92e-41: 133: 90.70		BRDT_MOUSE (299-559): 7.92e-28: 122: 20.80
+	Hs
		631388 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		BRD2_HUMAN (297-549): 3.19e-26: 116: 18.18
+	Hs
		917299 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		BRD3_HUMAN (306-466): 3.16e-26: 116: 23.60
+	Hs
		244235 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		BRD4_HUMAN (267-427): 1.9e-25: 114: 26.71
+	Hs
		917657 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		PHIP_HUMAN (314-685): 3.59e-20: 97.9: 12.30
+	Dm
		532730 H4_DROME (18-103): 2.42e-41: 133: 90.70		FSH_DROME (508-654): 1.71e-17: 89.6: 20.81
+	Sc
		356682 H4_YEAST (1-103): 5.28e-47: 147: 100.00		GCN5_YEAST (124-255): 2.17e-09: 62: 31.82
+	Hs
		918100 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		BAZ2B_HUMAN (307-420): 7.75e-13: 74.3: 39.47
+	Hs
		917170 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		EP300_HUMAN (303-417): 1.53e-09: 63.5: 37.61