Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: CENPA (P36012)
Histone H3-like centromeric protein CSE4 (CENP-A homolog) (CENPA homolog) (Chromosome segregation protein 4)
Gene: CSE4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 30381395, 17634282, 28980861, 31112132, 19782029, 37506202, 31578520, 38038247, 21070971, 21816344, 22199229
Identification Methods x-ray crystallography, two hybrid, affinity chromatography technology, biochemical, pull down
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CENP-T_C~Histone
Common GO terms GO:0005634 - nucleus
GO:0030527 - structural constituent of chromatin
GO:0046982 - protein heterodimerization activity
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 103
Sc

1 229
+ Kl
+ Ce
+ Hs
+ Mm
+ Hs
+ Xl
+ Xl
+ Hs
+ Hs
+ Mm
+ Mm
+ Ce
+ Hs
+ Sc
+ Sp
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024