Protein: BRR2
Pre-mRNA-splicing factor brr2 (EC 3.6.4.13) (Pre-mRNA-splicing factor spp41) (Pre-mRNA-splicing helicase BRR2)

Gene: BRR2
Organism: Schizosaccharomyces pombe 972h-
Interactions: 53
UniProt ID: Q9UT24

Gene Ontology (top 5):
GO:0000388 - spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
GO:0000393 - spliceosomal conformational changes to generate catalytic conformation
GO:0003676 - nucleic acid binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

143211

YE02
Uncharacterized helicase C17H9.02

4

14

Small-scale

0.887

High

144138

PRP19
Pre-mRNA-processing factor 19

2

20

High-throughput

0.789

High

1358073

YKR3
G-patch domain-containing protein C1486.03

2

18

Small-scale

0.757

High

1015544

PRP1
Pre-mRNA-splicing factor prp1

2

20

Small-scale

0.754

High

1336818

YK99
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase C20H4.09

2

20

High-throughput

0.754

High

765731

CEF1
Pre-mRNA-splicing factor cdc5

4

11

Small-scale

0.666

High

144966

SPP42
Pre-mRNA-splicing factor spp42

1

8

High-throughput

0.618

High

194934

DHX15
Probable pre-mRNA-splicing factor ATP-dependent RNA helicase prp43

1

20

High-throughput

0.618

High

195197

PRP17
Pre-mRNA-processing factor 17

2

20

High-throughput

0.611

High

953381

CWC2
Pre-mRNA-splicing factor cwf2

2

16

High-throughput

0.611

High

1358074

RED1
NURS complex subunit red1

2

3

Small-scale

0.611

High

142786

YF28
Uncharacterized protein C17A2.08c

2

1

Small-scale

0.586

High

953585

CLF1
Pre-mRNA-splicing factor cwf4

2

20

Small-scale

0.586

High

1350745

YK24
Uncharacterized protein C140.04

2

1

Small-scale

0.586

High

144438

SDE2
Splicing regulator sde2

2

2

Small-scale

0.584

High

194995

NRDE2
Protein NRDE2 homolog

2

2

Small-scale

0.584

High

251899

CWF14
Pre-mRNA-splicing factor cwf14

2

3

Small-scale

0.584

High

292966

SN114
Pre-mRNA-splicing factor cwf10

2

11

High-throughput

0.584

High

1319492

YN55
Uncharacterized WD repeat-containing protein C713.05

2

20

High-throughput

0.584

High

1336828

YK96
Uncharacterized protein C20H4.06c

2

1

High-throughput

0.584

High

1358048

RU2A
U2 small nuclear ribonucleoprotein A'

2

8

High-throughput

0.584

High

999737

DRE4
Pre-mRNA-splicing factor dre4

1

9

High-throughput

0.536

High

1350793

YLK3
Uncharacterized protein C1782.03

1

3

High-throughput

0.489

High

142005

PRP46
Pre-mRNA-splicing factor prp5

1

20

High-throughput

0.479

High

142680

NAB2
Nuclear polyadenylated RNA-binding protein nab2

1

2

Small-scale

0.479

High

144213

SMD2
Small nuclear ribonucleoprotein Sm D2

1

14

High-throughput

0.479

High

145833

EF2
Elongation factor 2

1

11

High-throughput

0.479

High

193913

SMD1
Small nuclear ribonucleoprotein Sm D1

1

20

High-throughput

0.479

High

223532

SYF2
Pre-mRNA-splicing factor syf2

1

1

High-throughput

0.479

High

223679

ESS2
Stress response protein bis1

1

1

High-throughput

0.479

High

223715

SLT11
Pre-mRNA-splicing factor cwf5

1

11

High-throughput

0.479

High

223786

HSP72
Probable heat shock protein ssa2

1

13

High-throughput

0.479

High

251368

ISY1
Pre-mRNA-splicing factor cwf12

1

3

High-throughput

0.479

High

252602

RUXG
Small nuclear ribonucleoprotein G

1

20

High-throughput

0.479

High

293133

PIR2
NURS complex subunit pir2

1

2

High-throughput

0.479

High

293531

CWF11
Pre-mRNA-splicing factor cwf11

1

5

High-throughput

0.479

High

293830

JHD1
Putative JmjC domain-containing histone demethylation protein 1

1

5

High-throughput

0.479

High

293870

CWF17
Pre-mRNA-splicing factor cwf17

1

20

High-throughput

0.479

High

678721

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

12

High-throughput

0.479

High

740416

DIS3
Exosome complex exonuclease dis3

1

6

High-throughput

0.479

High

772809

ENO11
Enolase 1-1

1

2

High-throughput

0.479

High

784800

HSP90
Heat shock protein 90 homolog

1

9

High-throughput

0.479

High

945020

CWC15
Pre-mRNA-splicing factor cwf15

1

1

High-throughput

0.479

High

945124

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

1

High-throughput

0.479

High

1000045

PRP45
Pre-mRNA-processing protein 45

1

10

High-throughput

0.479

High

1000072

CWF19
Pre-mRNA-splicing factor cwf19

1

1

High-throughput

0.479

High

1013610

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

20

High-throughput

0.479

High

1185660

RU2B
Probable U2 small nuclear ribonucleoprotein B''

1

20

High-throughput

0.479

High

1350845

SYF1
Pre-mRNA-splicing factor cwf3

1

20

High-throughput

0.479

High

1358038

SPF27
Pre-mRNA-splicing factor cwf7

1

1

High-throughput

0.479

High

1358075

CWF18
Pre-mRNA-splicing factor cwf18

1

1

High-throughput

0.479

High

1358076

SMD3
Small nuclear ribonucleoprotein Sm D3

1

20

High-throughput

0.479

High

144348

YERE
WW domain-containing protein C2F3.14c

1

0

High-throughput

0.458

High


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Last updated: 15 Jul 2024