HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: NHP10 (Q03435)
Non-histone protein 10 (High mobility group protein 2)
Gene: NHP10

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	16429126, 24034245
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 203
+	Hs
		917780 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CIC_HUMAN (44-201): 6.64e-29: 114: 16.76
+	Hs
		297483 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		TOX4_HUMAN (51-199): 4.76e-28: 112: 18.82
+	Mm
		818683 H4_MOUSE (18-103): 1.92e-41: 133: 90.70		SOX2_MOUSE (62-178): 1.12e-28: 110: 14.88
+	Sc
		356198 H4_YEAST (1-103): 5.28e-47: 147: 100.00		NHP6A_YEAST (78-162): 3.8e-25: 95.6: 31.46
+	Sc
		356199 H4_YEAST (1-103): 5.28e-47: 147: 100.00		NHP6B_YEAST (78-162): 4.26e-25: 95.6: 32.58
+	Hs
		917167 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		SSRP1_HUMAN (72-186): 2.34e-26: 107: 21.85
+	Ce
		136663 H4_CAEEL (18-103): 1.71e-41: 133: 89.54		SSP1B_CAEEL (90-192): 1.05e-25: 105: 27.62
+	Hs
		918056 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HM20B_HUMAN (68-196): 1.37e-26: 105: 19.55
+	Hs
		175766 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HMGB3_HUMAN (90-160): 1.02e-23: 94.9: 32.00
+	Hs
		449647 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HMGB1_HUMAN (80-160): 1.31e-19: 84.5: 31.77
+	Hs
		643301 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HMGB2_HUMAN (92-160): 6.72e-16: 74.5: 27.40
+	Ce
		784738 H4_CAEEL (18-103): 1.71e-41: 133: 89.54		SSP1A_CAEEL (92-159): 1.74e-12: 67.1: 31.43