Interactor 1: CRYAA (P02489)
Alpha-crystallin A chain (Heat shock protein beta-4) (HspB4) (Heat shock protein family B member 4) [Cleaved into: Alpha-crystallin A(1-172); Alpha-crystallin A(1-168); Alpha-crystallin A(1-162)]
Gene: CRYAA

Interactor 2: V9HW27 (V9HW27)
Alpha-crystallin B chain (Alpha(B)-crystallin)
Gene: HEL-S-101

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 25416956
Identification Methods two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Crystallin~Crystallin, Crystallin~HSP20, HSP20~HSP20
Common GO terms GO:0002088 - lens development in camera-type eye
GO:0005212 - structural constituent of eye lens
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0009408 - response to heat
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 173
Hs

1 175
+ Hs
+ Bt
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024