Protein: HSP7C
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8)

Gene: HSP7C, Hspa8
Organism: Mus musculus
Interactions: 99
UniProt ID: P63017

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0001786 - phosphatidylserine binding
GO:0001822 - kidney development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

989295

CHIP
E3 ubiquitin-protein ligase CHIP

2

20

Small-scale

0.776

High

954999

DNJC5
DnaJ homolog subfamily C member 5

1

20

Small-scale

0.724

High

989266

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

20

Small-scale

0.724

High

312228

KLC1
Kinesin light chain 1

1

7

Small-scale

0.691

High

989263

NPHP3
Nephrocystin-3

1

7

High-throughput

0.691

High

989233

HSP7C
Heat shock cognate 71 kDa protein

1

12

Small-scale

0.647

High

989252

MEF2D
Myocyte-specific enhancer factor 2D

2

2

Small-scale

0.629

High

989242

KCMA1
Calcium-activated potassium channel subunit alpha-1

2

10

Small-scale

0.628

High

989288

BAG3
BAG family molecular chaperone regulator 3

1

20

Small-scale

0.618

High

108599

G3X9H5
Huntingtin

2

5

Small-scale

0.584

High

530769

TAU
Microtubule-associated protein tau

2

13

Small-scale

0.584

High

989260

NEB2
Neurabin-2

2

10

High-throughput

0.584

High

989273

BAG5
BAG family molecular chaperone regulator 5

1

20

Small-scale

0.575

High

954355

SNP25
Synaptosomal-associated protein 25

1

1

Small-scale

0.561

High

671885

CCND1
G1/S-specific cyclin-D1

1

4

Small-scale

0.536

High

989248

MKS1
Tectonic-like complex member MKS1

1

1

High-throughput

0.536

High

989255

CE290
Centrosomal protein of 290 kDa

1

10

High-throughput

0.536

High

989267

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

3

High-throughput

0.536

High

989274

AHI1
Jouberin

1

14

High-throughput

0.536

High

989280

RING2
E3 ubiquitin-protein ligase RING2

1

10

Small-scale

0.536

High

989285

TSC1
Hamartin

1

9

High-throughput

0.536

High

989291

NPHP1
Nephrocystin-1

1

1

High-throughput

0.536

High

989272

TTC23
Tetratricopeptide repeat protein 23

1

0

High-throughput

0.517

High

851830

PLIN2
Perilipin-2

1

3

Small-scale

0.515

High

59598

A2AM57
Inversin

1

7

High-throughput

0.489

High

97397

PRRT2
Proline-rich transmembrane protein 2

1

2

High-throughput

0.479

High

147482

DPYL2
Dihydropyrimidinase-related protein 2

1

4

High-throughput

0.479

High

598660

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

Small-scale

0.479

High

648039

MYD88
Myeloid differentiation primary response protein MyD88

1

6

Small-scale

0.479

High

688450

TWST1
Twist-related protein 1

1

2

High-throughput

0.479

High

700337

BRAF
Serine/threonine-protein kinase B-raf

1

13

High-throughput

0.479

High

718972

CDK4
Cyclin-dependent kinase 4

1

6

Small-scale

0.479

High

771450

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

2

High-throughput

0.479

High

813539

CDN1A
Cyclin-dependent kinase inhibitor 1

1

4

Small-scale

0.479

High

872966

SOX2
Transcription factor SOX-2

1

4

High-throughput

0.479

High

927682

ATX1
Ataxin-1

1

5

High-throughput

0.479

High

944130

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

6

Small-scale

0.479

High

947655

NPHP4
Nephrocystin-4

1

5

High-throughput

0.479

High

972197

1433E
14-3-3 protein epsilon

1

7

High-throughput

0.479

High

981214

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

3

High-throughput

0.479

High

989234

H31
Histone H3.1

1

8

Small-scale

0.479

High

989235

TRAF6
TNF receptor-associated factor 6

1

20

Small-scale

0.479

High

989236

ERG
Transcriptional regulator ERG

1

6

Small-scale

0.479

High

989237

CBX1
Chromobox protein homolog 1

1

3

High-throughput

0.479

High

989239

H33
Histone H3.3

1

8

Small-scale

0.479

High

989245

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

6

High-throughput

0.479

High

989249

PPP5
Serine/threonine-protein phosphatase 5

1

14

High-throughput

0.479

High

989250

KCNA5
Potassium voltage-gated channel subfamily A member 5

1

7

Small-scale

0.479

High

989253

INADL
InaD-like protein

1

8

Small-scale

0.479

High

989254

TFE3
Transcription factor E3

1

3

High-throughput

0.479

High

989257

TEDC2
Tubulin epsilon and delta complex protein 2

1

1

High-throughput

0.479

High

989258

Q6GTZ3
Idb1 protein

1

2

Small-scale

0.479

High

989259

KDM2B
Lysine-specific demethylase 2B

1

5

Small-scale

0.479

High

989261

SPOP
Speckle-type POZ protein

1

2

High-throughput

0.479

High

989262

UHRF2
E3 ubiquitin-protein ligase UHRF2

1

6

Small-scale

0.479

High

989264

FACD2
Fanconi anemia group D2 protein homolog

1

4

High-throughput

0.479

High

989276

EED
Polycomb protein EED

1

11

High-throughput

0.479

High

989277

HSPB2
Heat shock protein beta-2

1

11

High-throughput

0.479

High

989278

FBX32
F-box only protein 32

1

2

High-throughput

0.479

High

989281

ATX3
Ataxin-3

1

5

Small-scale

0.479

High

989283

PLIN3
Perilipin-3

1

3

Small-scale

0.479

High

989284

Q9DCC5
Cbx3 protein

1

3

High-throughput

0.479

High

989289

TLR4
Toll-like receptor 4

1

7

Small-scale

0.479

High

989290

CAF1A
Chromatin assembly factor 1 subunit A

1

4

High-throughput

0.479

High

989292

UBQL2
Ubiquilin-2

1

8

Small-scale

0.479

High

989296

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

20

Small-scale

0.479

High

989297

IKBA
NF-kappa-B inhibitor alpha

1

20

Small-scale

0.479

High

989298

KCNQ2
Potassium voltage-gated channel subfamily KQT member 2

1

8

High-throughput

0.479

High

940343

CIDEC
Lipid transferase CIDEC

1

0

Small-scale

0.458

High

989243

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.458

High

989268

CBAR1
CBY1-interacting BAR domain-containing protein 1

1

0

High-throughput

0.458

High

989271

KAT5
Histone acetyltransferase KAT5

1

0

Small-scale

0.458

High

989287

ZFN2A
AN1-type zinc finger protein 2A

1

0

Small-scale

0.458

High

204791

ST2B1
Sulfotransferase 2B1

1

1

Small-scale

0.445

High

237358

ILK
Scaffold protein ILK

1

6

Small-scale

0.445

High

313292

INVS
Inversin

1

7

High-throughput

0.445

High

772544

IRS1
Insulin receptor substrate 1

1

4

Small-scale

0.445

High

989238

H32
Histone H3.2

1

8

Small-scale

0.445

High

989240

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

1

High-throughput

0.445

High

989244

CBLB
E3 ubiquitin-protein ligase CBL-B

1

4

High-throughput

0.445

High

989246

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

4

High-throughput

0.445

High

989247

CC88B
Coiled-coil domain-containing protein 88B

1

4

Small-scale

0.445

High

989251

DLG4
Disks large homolog 4

1

4

High-throughput

0.445

High

989256

Q6AXH7
Histone-lysine N-methyltransferase EZH2

1

3

High-throughput

0.445

High

989270

FTM
Protein fantom

1

11

High-throughput

0.445

High

989294

B9D1
B9 domain-containing protein 1

1

1

Small-scale

0.445

High

97586

E9PV60
WD repeat and FYVE domain containing 4

1

10

High-throughput

0.437

High

398289

CFAD
Complement factor D

1

2

High-throughput

0.437

High

989265

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

12

High-throughput

0.437

High

989282

Q9D2V3
Progranulin

1

3

High-throughput

0.437

High

989286

TLR9
Toll-like receptor 9

1

6

Small-scale

0.437

High

989293

FZR1
Fizzy-related protein homolog

1

20

High-throughput

0.437

High

905807

CAV3
Caveolin-3

1

0

High-throughput

0.426

High

989241

KCRB
Creatine kinase B-type

1

0

Small-scale

0.426

High

989269

RD3
Protein RD3

1

0

Small-scale

0.426

High

694297

LIPC
Hepatic triacylglycerol lipase

1

0

Small-scale

0.249

Low

989275

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.249

Low

989279

Q9CPX4
Ferritin

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025