HitPredict

Interactor 1: K2C6A (P02538)
Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK-6A) (Cytokeratin-6D) (CK-6D) (Keratin-6A) (K6A) (Type-II keratin Kb6) (allergen Hom s 5)
Gene: KRT6A

Interactor 2: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	24623722
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005200 - structural constituent of cytoskeleton GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 564 Hs			1 664
+	Hs
		280772 K2C3_HUMAN (135-479): 1.83e-179: 521: 80.40		KRT36_HUMAN (31-457): 9.65e-119: 364: 23.83
+	Hs
		280777 K22E_HUMAN (135-479): 3.33e-173: 506: 72.75		KRT36_HUMAN (31-457): 9.65e-119: 364: 23.83
+	Hs
		280770 K2C8_HUMAN (135-511): 1.1e-163: 476: 68.70		KRT36_HUMAN (31-457): 9.65e-119: 364: 23.83
+	Hs
		280768 K2C1_HUMAN (128-494): 4.07e-107: 336: 73.30		KRT36_HUMAN (31-457): 9.65e-119: 364: 23.83
+	Hs
		318771 K2C3_HUMAN (135-479): 1.83e-179: 521: 80.40		K2C75_HUMAN (23-390): 1.2e-45: 172: 23.85
+	Hs
		517752 K2C3_HUMAN (135-479): 1.83e-179: 521: 80.40		K1H2_HUMAN (30-387): 6.02e-43: 162: 23.18
+	Hs
		280765 K2C75_HUMAN (3-564): 4.11e-101: 318: 67.79		KRT36_HUMAN (31-457): 9.65e-119: 364: 23.83
+	Hs
		517773 K2C3_HUMAN (135-479): 1.83e-179: 521: 80.40		KRT35_HUMAN (30-387): 1.7e-41: 158: 24.58
+	Hs
		729086 K22E_HUMAN (135-479): 3.33e-173: 506: 72.75		K1H2_HUMAN (30-387): 6.02e-43: 162: 23.18
+	Hs
		729145 K22E_HUMAN (135-479): 3.33e-173: 506: 72.75		KRT35_HUMAN (30-387): 1.7e-41: 158: 24.58
+	Hs
		409072 K2C8_HUMAN (135-511): 1.1e-163: 476: 68.70		K1H2_HUMAN (30-387): 6.02e-43: 162: 23.18
+	Hs
		409184 K2C8_HUMAN (135-511): 1.1e-163: 476: 68.70		KRT35_HUMAN (30-387): 1.7e-41: 158: 24.58
+	Hs
		408979 K2C8_HUMAN (135-511): 1.1e-163: 476: 68.70		VIME_HUMAN (27-389): 3.94e-31: 129: 28.93
+	Hs
		408991 K2C8_HUMAN (135-511): 1.1e-163: 476: 68.70		GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43
+	Hs
		422128 K2C7_HUMAN (103-534): 9.71e-159: 463: 63.99		NFL_HUMAN (28-433): 1.96e-26: 115: 27.07
+	Hs
		380657 K2C1_HUMAN (128-494): 4.07e-107: 336: 73.30		KRT35_HUMAN (30-387): 1.7e-41: 158: 24.58
+	Hs
		318765 K2C75_HUMAN (3-564): 4.11e-101: 318: 67.79		K2C75_HUMAN (23-390): 1.2e-45: 172: 23.85
+	Hs
		380550 K2C1_HUMAN (128-494): 4.07e-107: 336: 73.30		GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43
+	Hs
		318768 K2C75_HUMAN (3-564): 4.11e-101: 318: 67.79		VIME_HUMAN (27-389): 3.94e-31: 129: 28.93
+	Hs
		318775 K2C75_HUMAN (3-564): 4.11e-101: 318: 67.79		DESM_HUMAN (27-389): 6.1e-28: 119: 30.03