Protein: G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2 (GAPDH 2) (EC 1.2.1.12) (Triose-phosphate dehydrogenase 1)

Gene: G3P2, TDH2
Organism: Saccharomyces cerevisiae S288C
Interactions: 181
UniProt ID: P00358

Gene Ontology (top 5):
GO:0004365 - glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005811 - lipid droplet

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

358912

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

2

15

High-throughput

0.776

High

358911

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

2

15

Small-scale

0.754

High

358923

HSP82
ATP-dependent molecular chaperone HSP82

3

8

High-throughput

0.658

High

359022

GPX3
Glutathione peroxidase-like peroxiredoxin HYR1

2

2

Small-scale

0.624

High

358970

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

2

1

High-throughput

0.621

High

359068

YMF3
Uncharacterized protein YML053C

3

0

High-throughput

0.620

High

358910

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

14

High-throughput

0.618

High

359056

GCN5
Histone acetyltransferase GCN5

2

5

High-throughput

0.601

High

359046

RHO5
GTP-binding protein RHO5

2

2

Small-scale

0.594

High

359008

RPN10
26S proteasome regulatory subunit RPN10

2

1

Small-scale

0.584

High

359021

DSN1
Kinetochore-associated protein DSN1

2

2

High-throughput

0.584

High

359028

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.584

High

358924

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.536

High

358958

BIP
Endoplasmic reticulum chaperone BiP

1

7

High-throughput

0.536

High

358975

SGF29
SAGA complex subunit SGF29

1

1

High-throughput

0.536

High

358977

AHC2
ADA histone acetyltransferase complex component 2

1

1

High-throughput

0.536

High

358988

HSP7F
Heat shock protein homolog SSE1

1

14

High-throughput

0.536

High

358992

UFD4
Ubiquitin fusion degradation protein 4

1

3

High-throughput

0.536

High

358996

SPT7
SAGA complex subunit SPT7

1

6

High-throughput

0.536

High

359002

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

7

High-throughput

0.536

High

359010

SPT8
SAGA complex subunit SPT8

1

1

High-throughput

0.536

High

359034

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

1

High-throughput

0.536

High

359036

SPT20
SAGA complex subunit SPT20

1

1

High-throughput

0.536

High

359037

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

1

High-throughput

0.536

High

359043

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.536

High

359051

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

High-throughput

0.536

High

359052

ADA2
SAGA complex subunit ADA2

1

2

High-throughput

0.536

High

359069

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

1

High-throughput

0.536

High

359088

SUS1
SAGA complex subunit SUS1

1

1

High-throughput

0.536

High

358920

THDH
Threonine dehydratase, mitochondrial

1

2

High-throughput

0.515

High

358937

PBS2
MAP kinase kinase PBS2

1

7

High-throughput

0.515

High

358948

RAD50
DNA repair protein RAD50

1

2

High-throughput

0.515

High

358951

DPOLA
DNA polymerase alpha catalytic subunit A

1

2

High-throughput

0.515

High

358956

HSC82
ATP-dependent molecular chaperone HSC82

1

8

High-throughput

0.515

High

358965

DPOE
DNA polymerase epsilon catalytic subunit A

1

2

High-throughput

0.515

High

358969

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.515

High

359001

SWD3
COMPASS component SWD3

1

6

High-throughput

0.515

High

359057

VPS71
Vacuolar protein sorting-associated protein 71

1

1

High-throughput

0.515

High

359082

ULA1
NEDD8-activating enzyme E1 regulatory subunit

1

1

High-throughput

0.515

High

359084

ENG2
Glucan endo-1,3-beta-D-glucosidase 2

1

1

High-throughput

0.515

High

359012

GEM1
Mitochondrial Rho GTPase 1

1

0

High-throughput

0.513

High

359039

SGF73
SAGA complex subunit SGF73

1

0

High-throughput

0.513

High

359061

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

0

High-throughput

0.513

High

358942

SSBP1
Single-stranded nucleic acid-binding protein

1

3

High-throughput

0.501

High

358934

IF4E
Eukaryotic translation initiation factor 4E

1

1

High-throughput

0.500

High

358936

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

3

High-throughput

0.500

High

358949

EI2BD
Translation initiation factor eIF2B subunit delta

1

4

High-throughput

0.500

High

358953

EI2BA
Translation initiation factor eIF2B subunit alpha

1

4

High-throughput

0.500

High

358961

PHO85
Cyclin-dependent protein kinase PHO85

1

10

High-throughput

0.500

High

358963

PRP6
Pre-mRNA-splicing factor 6

1

3

High-throughput

0.500

High

358964

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

1

1

High-throughput

0.500

High

358973

RV161
Reduced viability upon starvation protein 161

1

1

High-throughput

0.500

High

358985

MKK2
MAP kinase kinase MKK2/SSP33

1

6

High-throughput

0.500

High

358989

PP12
Serine/threonine-protein phosphatase PP1-2

1

2

High-throughput

0.500

High

358998

VPS21
Vacuolar protein sorting-associated protein 21

1

1

High-throughput

0.500

High

359000

CAF4
CCR4-associated factor 4

1

5

High-throughput

0.500

High

359003

IMB2
Importin subunit beta-2

1

2

High-throughput

0.500

High

359005

RCK1
Serine/threonine-protein kinase RCK1

1

6

High-throughput

0.500

High

359024

SA185
SIT4-associating protein SAP185

1

3

High-throughput

0.500

High

359029

SA155
SIT4-associating protein SAP155

1

3

High-throughput

0.500

High

359041

SSK2
MAP kinase kinase kinase SSK2

1

6

High-throughput

0.500

High

359049

RHO4
GTP-binding protein RHO4

1

1

High-throughput

0.500

High

359050

AP1M1
AP-1 complex subunit mu-1-I

1

7

High-throughput

0.500

High

359059

STE20
Serine/threonine-protein kinase STE20

1

6

High-throughput

0.500

High

359065

SPC24
Kinetochore protein SPC24

1

1

High-throughput

0.500

High

359086

ATG5
Autophagy protein 5

1

1

High-throughput

0.500

High

359089

AP2M
AP-2 complex subunit mu

1

7

High-throughput

0.500

High

359032

RAD17
DNA damage checkpoint control protein RAD17

1

0

High-throughput

0.493

High

359044

TOF1
Topoisomerase 1-associated factor 1

1

0

High-throughput

0.493

High

359058

THADA
tRNA

1

0

High-throughput

0.493

High

359072

MMS1
E3 ubiquitin-protein ligase linker protein MMS1

1

0

High-throughput

0.493

High

358967

SAN1
Protein SAN1

1

2

Small-scale

0.481

High

359020

ULP2
Ubiquitin-like-specific protease 2

1

5

High-throughput

0.481

High

359053

ULP1
Ubiquitin-like-specific protease 1

1

5

High-throughput

0.481

High

359073

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.479

High

358913

CCPR
Cytochrome c peroxidase, mitochondrial

1

2

Small-scale

0.479

High

358914

SODC
Superoxide dismutase [Cu-Zn]

1

3

High-throughput

0.479

High

358915

CDK1
Cyclin-dependent kinase 1

1

6

High-throughput

0.479

High

358916

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.479

High

358917

PGK
Phosphoglycerate kinase

1

4

High-throughput

0.479

High

358918

ENO1
Enolase 1

1

9

High-throughput

0.479

High

358919

ENO2
Enolase 2

1

9

High-throughput

0.479

High

358921

TPIS
Triosephosphate isomerase

1

2

High-throughput

0.479

High

358922

PMG1
Phosphoglycerate mutase 1

1

3

High-throughput

0.479

High

358925

HXKA
Hexokinase-1

1

3

High-throughput

0.479

High

358926

HXKB
Hexokinase-2

1

3

High-throughput

0.479

High

358928

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

3

Small-scale

0.479

High

358929

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

2

High-throughput

0.479

High

358931

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.479

High

358932

SNF1
Carbon catabolite-derepressing protein kinase

1

1

Small-scale

0.479

High

358933

KAD2
Adenylate kinase

1

1

High-throughput

0.479

High

358935

DHE4
NADP-specific glutamate dehydrogenase 1

1

1

High-throughput

0.479

High

358941

HSP77
Import motor subunit, mitochondrial

1

9

High-throughput

0.479

High

358947

G6PI
Glucose-6-phosphate isomerase

1

2

High-throughput

0.479

High

358950

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

358952

ALF
Fructose-bisphosphate aldolase

1

3

High-throughput

0.479

High

358954

CYPH
Peptidyl-prolyl cis-trans isomerase

1

2

High-throughput

0.479

High

358957

STI1
Heat shock protein STI1

1

8

High-throughput

0.479

High

358959

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

2

High-throughput

0.479

High

358960

FUS3
Mitogen-activated protein kinase FUS3

1

5

High-throughput

0.479

High

358962

ACON
Aconitate hydratase, mitochondrial

1

1

Small-scale

0.479

High

358966

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.479

High

358968

TKT1
Transketolase 1

1

2

High-throughput

0.479

High

358971

PSA2
Proteasome subunit alpha type-2

1

1

High-throughput

0.479

High

358972

SIS1
Protein SIS1

1

4

High-throughput

0.479

High

358976

GID7
GID complex subunit 7

1

4

High-throughput

0.479

High

358980

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

358981

BMH1
Protein BMH1

1

8

High-throughput

0.479

High

358982

DHOM
Homoserine dehydrogenase

1

1

High-throughput

0.479

High

358983

HS104
Heat shock protein 104

1

2

Small-scale

0.479

High

358984

EF1B
Elongation factor 1-beta

1

1

High-throughput

0.479

High

358986

ZUO1
Zuotin

1

4

Small-scale

0.479

High

358987

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

2

High-throughput

0.479

High

358990

SMY2
Protein SMY2

1

2

High-throughput

0.479

High

358993

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.479

High

358997

TCTP
Translationally-controlled tumor protein homolog

1

1

High-throughput

0.479

High

358999

MIC60
MICOS complex subunit MIC60

1

2

High-throughput

0.479

High

359004

GID4
GID complex substrate-recognition subunit 4

1

1

High-throughput

0.479

High

359007

RPN1
26S proteasome regulatory subunit RPN1

1

2

High-throughput

0.479

High

359009

CH10
10 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.479

High

359011

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.479

High

359017

MMF1
Protein MMF1, mitochondrial

1

1

High-throughput

0.479

High

359019

FIS1
Mitochondrial fission 1 protein

1

1

Small-scale

0.479

High

359025

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

1

High-throughput

0.479

High

359031

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.479

High

359038

VID30
GID complex subunit 1

1

4

High-throughput

0.479

High

359040

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

2

High-throughput

0.479

High

359045

GIS2
Zinc finger protein GIS2

1

3

High-throughput

0.479

High

359047

SAM50
Sorting assembly machinery 50 kDa subunit

1

2

High-throughput

0.479

High

359048

ORC1
Origin recognition complex subunit 1

1

4

High-throughput

0.479

High

359054

COFI
Cofilin

1

3

High-throughput

0.479

High

359055

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.479

High

359062

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.479

High

359064

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.479

High

359067

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

2

High-throughput

0.479

High

359070

EIS1
Eisosome protein 1

1

2

Small-scale

0.479

High

359071

PUR8
Adenylosuccinate lyase

1

2

High-throughput

0.479

High

359077

SGO1
Shugoshin

1

2

High-throughput

0.479

High

359080

YIG1
Protein YIG1

1

1

High-throughput

0.479

High

359085

NYV1
Vacuolar v-SNARE NYV1

1

1

High-throughput

0.479

High

359013

YEC3
Uncharacterized protein YEL023C

1

1

High-throughput

0.470

High

359074

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

1

6

High-throughput

0.470

High

359078

BUD7
Bud site selection protein 7

1

1

High-throughput

0.470

High

358927

RLA0
Large ribosomal subunit protein uL10

1

0

Small-scale

0.458

High

358930

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.458

High

358939

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

358945

MITF2
Mitochondrial translation factor 2

1

0

High-throughput

0.458

High

358955

TAL1
Transaldolase

1

0

High-throughput

0.458

High

359027

MID1
Stretch-activated cation channel MID1

1

0

Small-scale

0.458

High

359030

DUG1
Cys-Gly metallodipeptidase DUG1

1

0

High-throughput

0.458

High

359060

OYE2
NADPH dehydrogenase 2

1

0

High-throughput

0.458

High

359075

AVO1
Target of rapamycin complex 2 subunit AVO1

1

0

High-throughput

0.458

High

359076

ZEO1
Protein ZEO1

1

0

High-throughput

0.458

High

358991

SUI1
Eukaryotic translation initiation factor eIF-1

1

2

High-throughput

0.457

High

359026

COPB2
Coatomer subunit beta'

1

6

High-throughput

0.457

High

359081

TFB4
General transcription and DNA repair factor IIH subunit TFB4

1

1

Small-scale

0.457

High

358938

HSP73
Heat shock protein SSA3

1

10

High-throughput

0.445

High

358940

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

7

High-throughput

0.445

High

358943

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

358944

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

358946

SSB1
Ribosome-associated molecular chaperone SSB1

1

10

High-throughput

0.445

High

358978

KCC1
Calcium/calmodulin-dependent protein kinase I

1

1

High-throughput

0.445

High

359015

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

2

High-throughput

0.445

High

359016

SSB2
Ribosome-associated molecular chaperone SSB2

1

10

High-throughput

0.445

High

359018

6P21
6-phosphofructo-2-kinase 1

1

5

High-throughput

0.445

High

359035

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

2

High-throughput

0.445

High

359083

HFI1
SAGA complex subunit HFI1

1

2

High-throughput

0.445

High

358979

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.437

High

358995

IF4B
Eukaryotic translation initiation factor 4B

1

2

High-throughput

0.437

High

359006

GOSR1
Golgi SNAP receptor complex member 1

1

1

High-throughput

0.437

High

359023

RLP7
Ribosome biogenesis protein RLP7

1

2

High-throughput

0.437

High

359033

VATG
V-type proton ATPase subunit G

1

2

High-throughput

0.437

High

359042

COPA
Coatomer subunit alpha

1

5

High-throughput

0.437

High

359066

POB3
FACT complex subunit POB3

1

1

High-throughput

0.437

High

359079

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

359087

DBP10
ATP-dependent RNA helicase DBP10

1

4

High-throughput

0.437

High

358974

RAD51
DNA repair protein RAD51

1

0

High-throughput

0.269

Low

358994

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

1

0

High-throughput

0.269

Low

359014

RPN3
26S proteasome regulatory subunit RPN3

1

0

High-throughput

0.269

Low

359063

RKM2
Ribosomal lysine N-methyltransferase 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025