HitPredict

Interactor 1: K2C6A (P02538)
Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK-6A) (Cytokeratin-6D) (CK-6D) (Keratin-6A) (K6A) (Type-II keratin Kb6) (allergen Hom s 5)
Gene: KRT6A

Interactor 2: CBL (P22681)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 564 Hs			1 906
+	Hs
		517738 K2C3_HUMAN (135-479): 1.83e-179: 521: 80.40		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		610265 K22E_HUMAN (135-479): 3.33e-173: 506: 72.75		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		380560 K2C1_HUMAN (128-494): 4.07e-107: 336: 73.30		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		610513 KRT84_HUMAN (1-558): 6.5e-103: 324: 51.69		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		380445 K2C6B_HUMAN (1-499): 1.46e-91: 293: 98.60		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		610295 K2C6C_HUMAN (1-499): 3.56e-91: 292: 98.40		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		531534 K2C5_HUMAN (3-479): 1.58e-84: 276: 80.75		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		610433 K2C79_HUMAN (45-562): 4.1e-80: 262: 61.54		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		203197 K2C8_HUMAN (135-511): 1.1e-163: 476: 68.70		SYNJ1_HUMAN (542-897): 2.72e-14: 79.6: 10.22
+	Hs
		409194 K2C8_HUMAN (135-511): 1.1e-163: 476: 68.70		ASPP1_HUMAN (445-844): 1.47e-10: 67.3: 10.25
+	Hs
		580149 K2C4_HUMAN (1-488): 3.52e-75: 249: 64.75		ASPP1_HUMAN (445-844): 1.47e-10: 67.3: 10.25