Interactor 1: SPTA1 (P02549)
Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin)
Gene: SPTA1
Interactor 2: SPTB1 (P11277)
Spectrin beta chain, erythrocytic (Beta-I spectrin)
Gene: SPTB
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.84 | 1.00 | 0.920 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 1634521, 33961781, 8226774, 12820899, 20197550 |
| Identification Methods | unspecified method, affinity chromatography technology, experimental interaction detection, surface plasmon resonance, anti tag coimmunoprecipitation, x-ray crystallography, cosedimentation in solution, circular dichroism |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CH~EFhand_Ca_insen, EFhand_Ca_insen~Spectrin, CH~Spectrin, Spectrin~Spectrin |
| Common GO terms | GO:0005200 - structural constituent of cytoskeleton GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008091 - spectrin GO:0009898 - cytoplasmic side of plasma membrane and 8 others more... |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
